The Fibrodysplasia Ossificans Progressiva and Bone Scintigraphy
Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare autosomal dominant condition characterized by malformations of the big toes and progressive extra-skeletal ossifications in distinct anatomical patterns. In FOP, heterotopic ossification (HO) occurs episodically, resulting from sp...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SJORANM GmbH (Ltd.)
2024-04-01
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| Series: | Swiss Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://sjoranm.com/sjoranm/article/view/22 |
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| Summary: | Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare autosomal dominant condition characterized by malformations of the big toes and progressive extra-skeletal ossifications in distinct anatomical patterns. In FOP, heterotopic ossification (HO) occurs episodically, resulting from spontaneous flare-ups or trauma, leading to cumulative disability. Bone scintigraphy with 99mTc-MDP combined with SPECT-CT is instrumental in early detection, diagnosis, staging, and disease monitoring by highlighting HO sites.
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| ISSN: | 2813-7221 |