HLA-C*18:01 and KIR2DL2+C1 genetic variants are associated with low viral load in cART naïve HIV-infected adult Zimbabweans

HLA-C*18:01 and KIR2DL2+C1 genetic variants are associated with low viral load in cART naïve HIV-infected adult Zimbabweans

Introduction: Polymorphisms in killer cell immunoglobulin-like receptor (KIR) and human leukocyte antigen (HLA) gene families are implicated in differential outcomes of HIV infection. However, research findings on the influence of KIR and HLA-C polymorphism on HIV disease progression remain inconcl...

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Main Authors: Kudakwashe Mhandire, Mqondisi Tshabalala, Lynn Sodai Zijenah, Tommy Mlambo, Doreen Zvipo Mhandire, Cuthbert Musarurwa, Kerina Duri, Hilda Tendisa Matarira, Collet Dandara, Sarah L Rowland-Jones, Babill Stray-Pedersen
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2018-12-01
Series:Journal of Infection in Developing Countries
Subjects:
HLA
KIR
natural killer cells
HIV
viral load
Zimbabweans
Online Access:https://jidc.org/index.php/journal/article/view/10848
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