Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in Korea

Background This study investigated the prevalence of diabetes mellitus (DM) and impaired fasting glucose, as well as their management and comorbidities among older Korean adults. Methods Data from 269,447 individuals aged 65 years and older from the Korean National Health Insurance Service between 2...

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Main Authors: Kwang Joon Kim, Jeongmin Lee, Yang Sun Park, Yong-ho Lee, Kyeong Hye Park, Hee-Won Jung, Chang Oh Kim, Man Young Park, Hun-Sung Kim, Bong-Soo Cha
Format: Article
Language:English
Published: Korean Endocrine Society 2025-06-01
Series:Endocrinology and Metabolism
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Online Access:http://www.e-enm.org/upload/pdf/enm-2024-2173.pdf
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author Kwang Joon Kim
Jeongmin Lee
Yang Sun Park
Yong-ho Lee
Kyeong Hye Park
Hee-Won Jung
Chang Oh Kim
Man Young Park
Hun-Sung Kim
Bong-Soo Cha
author_facet Kwang Joon Kim
Jeongmin Lee
Yang Sun Park
Yong-ho Lee
Kyeong Hye Park
Hee-Won Jung
Chang Oh Kim
Man Young Park
Hun-Sung Kim
Bong-Soo Cha
author_sort Kwang Joon Kim
collection DOAJ
description Background This study investigated the prevalence of diabetes mellitus (DM) and impaired fasting glucose, as well as their management and comorbidities among older Korean adults. Methods Data from 269,447 individuals aged 65 years and older from the Korean National Health Insurance Service between 2000 and 2019 were analyzed to evaluate trends in DM prevalence, healthcare utilization, mortality, and complications. Results Among 269,447 individuals, 18.6% (n=50,159/269,447) were diagnosed with DM and 27.0% (n=72,670/269,447) had impaired fasting glucose. The DM group had the highest body mass index, waist circumference, and prevalence of current smokers (P<0.001) but not the highest hypertension prevalence. From 2010 to 2019, the prevalence of DM and impaired fasting glucose increased from 15.5% to 21.9% and from 26.0% to 30.6%, respectively. Cancer-related mortality in DM was 1.15 times higher than in those with normal glucose tolerance (P<0.001), and cardiovascular disease-related mortality was 1.32 times higher (P<0.001); all mortalities were higher in female participants. Myocardial infarction (hazard ratio [HR], 1.34; P<0.001), stroke (HR, 1.24; P<0.001), and heart failure (HR, 1.13; P<0.001) were significantly higher in those with DM. Conclusion This is the first study to investigate the prevalence of DM and related complications in older individuals based on longterm representative data in Korea. These results highlight the necessity for targeted interventions to enhance management and outcomes in this population.
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spelling doaj-art-3784b0e596d64f05b572cb2b2dca87f12025-08-20T02:37:36ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782025-06-0140344845810.3803/EnM.2024.21732585Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in KoreaKwang Joon Kim0Jeongmin Lee1Yang Sun Park2Yong-ho Lee3Kyeong Hye Park4Hee-Won Jung5Chang Oh Kim6Man Young Park7Hun-Sung Kim8Bong-Soo Cha9 Division of Geriatrics, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Division of Endocrinology and Metabolism, Department of Internal Medicine, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Division of Geriatrics, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea Division of Geriatrics, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Division of Geriatrics, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Digital Clinical Research Department, Korea Institute of Oriental Medicine, Daejeon, Korea Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, KoreaBackground This study investigated the prevalence of diabetes mellitus (DM) and impaired fasting glucose, as well as their management and comorbidities among older Korean adults. Methods Data from 269,447 individuals aged 65 years and older from the Korean National Health Insurance Service between 2000 and 2019 were analyzed to evaluate trends in DM prevalence, healthcare utilization, mortality, and complications. Results Among 269,447 individuals, 18.6% (n=50,159/269,447) were diagnosed with DM and 27.0% (n=72,670/269,447) had impaired fasting glucose. The DM group had the highest body mass index, waist circumference, and prevalence of current smokers (P<0.001) but not the highest hypertension prevalence. From 2010 to 2019, the prevalence of DM and impaired fasting glucose increased from 15.5% to 21.9% and from 26.0% to 30.6%, respectively. Cancer-related mortality in DM was 1.15 times higher than in those with normal glucose tolerance (P<0.001), and cardiovascular disease-related mortality was 1.32 times higher (P<0.001); all mortalities were higher in female participants. Myocardial infarction (hazard ratio [HR], 1.34; P<0.001), stroke (HR, 1.24; P<0.001), and heart failure (HR, 1.13; P<0.001) were significantly higher in those with DM. Conclusion This is the first study to investigate the prevalence of DM and related complications in older individuals based on longterm representative data in Korea. These results highlight the necessity for targeted interventions to enhance management and outcomes in this population.http://www.e-enm.org/upload/pdf/enm-2024-2173.pdfneoplasmscardiovascular diseasesdiabetes mellitusmortality
spellingShingle Kwang Joon Kim
Jeongmin Lee
Yang Sun Park
Yong-ho Lee
Kyeong Hye Park
Hee-Won Jung
Chang Oh Kim
Man Young Park
Hun-Sung Kim
Bong-Soo Cha
Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in Korea
Endocrinology and Metabolism
neoplasms
cardiovascular diseases
diabetes mellitus
mortality
title Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in Korea
title_full Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in Korea
title_fullStr Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in Korea
title_full_unstemmed Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in Korea
title_short Prevalence of Mortality and Vascular Complications in Older Patients with Diabetes in Korea
title_sort prevalence of mortality and vascular complications in older patients with diabetes in korea
topic neoplasms
cardiovascular diseases
diabetes mellitus
mortality
url http://www.e-enm.org/upload/pdf/enm-2024-2173.pdf
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