Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments

Liquid-state Overhauser Dynamic Nuclear Polarization (ODNP) is an emerging technique, aimed at shortening NMR experiment times. It achieves this by increasing the otherwise poor nuclear polarization at room temperature, by polarization transfer from excited electron spins. The present work explores...

Full description

Saved in:
Bibliographic Details
Main Author: Alex van der Ham
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Magnetic Resonance Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666441024000153
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850245234060951552
author Alex van der Ham
author_facet Alex van der Ham
author_sort Alex van der Ham
collection DOAJ
description Liquid-state Overhauser Dynamic Nuclear Polarization (ODNP) is an emerging technique, aimed at shortening NMR experiment times. It achieves this by increasing the otherwise poor nuclear polarization at room temperature, by polarization transfer from excited electron spins. The present work explores two ideas, aimed at achieving the optimal signal-to-noise per time unit for a given system, and quantitation of spectra showing a large disparity in ODNP enhancements at high magnetic fields (≥ 9.4 T). Both of these ideas are predicated on, perhaps counterintuitively, not allowing full dynamic nuclear polarization to build up, either by rapid rf pulsing, or gating of the microwave irradiation.
format Article
id doaj-art-37822bae8a744116a122399ffb1d0cd0
institution OA Journals
issn 2666-4410
language English
publishDate 2024-12-01
publisher Elsevier
record_format Article
series Journal of Magnetic Resonance Open
spelling doaj-art-37822bae8a744116a122399ffb1d0cd02025-08-20T01:59:31ZengElsevierJournal of Magnetic Resonance Open2666-44102024-12-012110016010.1016/j.jmro.2024.100160Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experimentsAlex van der Ham0Max Planck Institute for Multidisciplinary Sciences, Am Faßberg 11, 37077 Göttingen, GermanyLiquid-state Overhauser Dynamic Nuclear Polarization (ODNP) is an emerging technique, aimed at shortening NMR experiment times. It achieves this by increasing the otherwise poor nuclear polarization at room temperature, by polarization transfer from excited electron spins. The present work explores two ideas, aimed at achieving the optimal signal-to-noise per time unit for a given system, and quantitation of spectra showing a large disparity in ODNP enhancements at high magnetic fields (≥ 9.4 T). Both of these ideas are predicated on, perhaps counterintuitively, not allowing full dynamic nuclear polarization to build up, either by rapid rf pulsing, or gating of the microwave irradiation.http://www.sciencedirect.com/science/article/pii/S2666441024000153Dynamic nuclear polarization (dnp)QuantitationMicrowave gating
spellingShingle Alex van der Ham
Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments
Journal of Magnetic Resonance Open
Dynamic nuclear polarization (dnp)
Quantitation
Microwave gating
title Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments
title_full Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments
title_fullStr Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments
title_full_unstemmed Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments
title_short Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments
title_sort discontinuous hyperpolarization schemes in liquid state overhauser dynamic nuclear polarization experiments
topic Dynamic nuclear polarization (dnp)
Quantitation
Microwave gating
url http://www.sciencedirect.com/science/article/pii/S2666441024000153
work_keys_str_mv AT alexvanderham discontinuoushyperpolarizationschemesinliquidstateoverhauserdynamicnuclearpolarizationexperiments