Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020
Background Hypertension is a global health concern, and antihypertensive medications are vital for its management. This study examined evolving trends in antihypertensive medication usage among adults with hypertension from 1999 to 2020.Methods Data from 10 National Health and Nutrition Examination...
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Taylor & Francis Group
2025-12-01
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| Series: | Blood Pressure |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/08037051.2025.2506081 |
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| author | Junwen Wang Yuyang Ye Xuefeng Chen Xinru Hu Yong Peng |
| author_facet | Junwen Wang Yuyang Ye Xuefeng Chen Xinru Hu Yong Peng |
| author_sort | Junwen Wang |
| collection | DOAJ |
| description | Background Hypertension is a global health concern, and antihypertensive medications are vital for its management. This study examined evolving trends in antihypertensive medication usage among adults with hypertension from 1999 to 2020.Methods Data from 10 National Health and Nutrition Examination Survey (NHANES) survey cycles were obtained for adults aged 18 years and older with hypertension. The study analysed demographic, drug classification and demographic variables. All statistical analyses, including logistic regression, were used to assess trends.Results Among 18,221 hypertensive participants, diverse characteristics were observed. The use of angiotensin-converting enzyme inhibitors increased from 26.18% in 1999 to 32.76% in 2020 (linear p = 0.001). Angiotensin receptor blocker use rose from 10.36% to 26.57%. Beta blocker usage increased from 28.98% in 1999 to 42.50% in 2010, plateauing at approximately 40% from 2011 to 2020 (quadratic p < 0.001). Calcium channel blocker (CCB) utilisation increased from 16.70% in 1999 to 20.46% in 2020 (linear p < 0.001). Diuretic (DU) use decreased from 32.70% in 1999 to 26.34% in 2020 (quadratic p = 0.009). The use of antihypertensive medications varies across different demographic groups and comorbidities.Conclusions ACEI, ARB and CCB usage increased, while DU usage decreased. BB utilisation stabilised at a high rate. Antihypertensive drug use displayed diverse trends across demographic groups and comorbidities. |
| format | Article |
| id | doaj-art-377e829dcf1b4ed4abe67ea55c4470a8 |
| institution | Kabale University |
| issn | 0803-7051 1651-1999 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
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| series | Blood Pressure |
| spelling | doaj-art-377e829dcf1b4ed4abe67ea55c4470a82025-08-20T03:47:44ZengTaylor & Francis GroupBlood Pressure0803-70511651-19992025-12-0134110.1080/08037051.2025.2506081Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020Junwen Wang0Yuyang Ye1Xuefeng Chen2Xinru Hu3Yong Peng4Department of Cardiology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, ChinaBackground Hypertension is a global health concern, and antihypertensive medications are vital for its management. This study examined evolving trends in antihypertensive medication usage among adults with hypertension from 1999 to 2020.Methods Data from 10 National Health and Nutrition Examination Survey (NHANES) survey cycles were obtained for adults aged 18 years and older with hypertension. The study analysed demographic, drug classification and demographic variables. All statistical analyses, including logistic regression, were used to assess trends.Results Among 18,221 hypertensive participants, diverse characteristics were observed. The use of angiotensin-converting enzyme inhibitors increased from 26.18% in 1999 to 32.76% in 2020 (linear p = 0.001). Angiotensin receptor blocker use rose from 10.36% to 26.57%. Beta blocker usage increased from 28.98% in 1999 to 42.50% in 2010, plateauing at approximately 40% from 2011 to 2020 (quadratic p < 0.001). Calcium channel blocker (CCB) utilisation increased from 16.70% in 1999 to 20.46% in 2020 (linear p < 0.001). Diuretic (DU) use decreased from 32.70% in 1999 to 26.34% in 2020 (quadratic p = 0.009). The use of antihypertensive medications varies across different demographic groups and comorbidities.Conclusions ACEI, ARB and CCB usage increased, while DU usage decreased. BB utilisation stabilised at a high rate. Antihypertensive drug use displayed diverse trends across demographic groups and comorbidities.https://www.tandfonline.com/doi/10.1080/08037051.2025.2506081HypertensionAntihypertensive MedicationTrend AnalysisEpidemiologyRace and EthnicityDemographic Characteristics |
| spellingShingle | Junwen Wang Yuyang Ye Xuefeng Chen Xinru Hu Yong Peng Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020 Blood Pressure Hypertension Antihypertensive Medication Trend Analysis Epidemiology Race and Ethnicity Demographic Characteristics |
| title | Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020 |
| title_full | Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020 |
| title_fullStr | Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020 |
| title_full_unstemmed | Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020 |
| title_short | Diverse trends in antihypertensive medication usage among U.S. Adults with hypertension by socioeconomic status and comorbidities, 1999–2020 |
| title_sort | diverse trends in antihypertensive medication usage among u s adults with hypertension by socioeconomic status and comorbidities 1999 2020 |
| topic | Hypertension Antihypertensive Medication Trend Analysis Epidemiology Race and Ethnicity Demographic Characteristics |
| url | https://www.tandfonline.com/doi/10.1080/08037051.2025.2506081 |
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