Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal
Aim: This study aimed to compare methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization in people living with HIV (PLHIV) and healthy people from Kathmandu. Methods: MRSA isolated from 400 nasal swabs was screened using a cefoxitin disc and confirmed by the presence of the mecA gene....
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-02-01
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| Series: | Future Science OA |
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| Online Access: | https://www.future-science.com/doi/10.2144/fsoa-2021-0103 |
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| author | Samjhana Kapali Anil Pokhrel Anup Bastola Reshma Tuladhar Dev Raj Joshi |
| author_facet | Samjhana Kapali Anil Pokhrel Anup Bastola Reshma Tuladhar Dev Raj Joshi |
| author_sort | Samjhana Kapali |
| collection | DOAJ |
| description | Aim: This study aimed to compare methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization in people living with HIV (PLHIV) and healthy people from Kathmandu. Methods: MRSA isolated from 400 nasal swabs was screened using a cefoxitin disc and confirmed by the presence of the mecA gene. Results: MRSA nasal carriers among the PLHIV and control cohorts were 3.5% (7 out of 200) and 5.0% (10 out of 200), respectively. All the MRSA from PLHIV and most of MRSA from healthy controls were PVL positive. Longer duration of antiretroviral therapy significantly reduces the risk of MRSA nasal colonization in PLHIV. Conclusion: There is no significant difference in MRSA nasal colonization in PLHIV and healthy controls in this study region. |
| format | Article |
| id | doaj-art-37771dabd6874be889ddfaae33d1ea63 |
| institution | OA Journals |
| issn | 2056-5623 |
| language | English |
| publishDate | 2022-02-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj-art-37771dabd6874be889ddfaae33d1ea632025-08-20T02:25:48ZengTaylor & Francis GroupFuture Science OA2056-56232022-02-018210.2144/fsoa-2021-0103Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, NepalSamjhana Kapali0Anil Pokhrel1Anup Bastola2Reshma Tuladhar3Dev Raj Joshi41Central Department of Microbiology, Institute of Science & Technology, Tribhuvan University, Kathmandu, 44613, Nepal1Central Department of Microbiology, Institute of Science & Technology, Tribhuvan University, Kathmandu, 44613, Nepal2Department of Dermatology & Sexually Transmitted Infections, Sukraraj Tropical & Infectious Disease Hospital, Kathmandu, 44600, Nepal1Central Department of Microbiology, Institute of Science & Technology, Tribhuvan University, Kathmandu, 44613, Nepal1Central Department of Microbiology, Institute of Science & Technology, Tribhuvan University, Kathmandu, 44613, NepalAim: This study aimed to compare methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization in people living with HIV (PLHIV) and healthy people from Kathmandu. Methods: MRSA isolated from 400 nasal swabs was screened using a cefoxitin disc and confirmed by the presence of the mecA gene. Results: MRSA nasal carriers among the PLHIV and control cohorts were 3.5% (7 out of 200) and 5.0% (10 out of 200), respectively. All the MRSA from PLHIV and most of MRSA from healthy controls were PVL positive. Longer duration of antiretroviral therapy significantly reduces the risk of MRSA nasal colonization in PLHIV. Conclusion: There is no significant difference in MRSA nasal colonization in PLHIV and healthy controls in this study region.https://www.future-science.com/doi/10.2144/fsoa-2021-0103mecAMRSAmulti-drug resistancePLHIVPVLStaphylococcus aureus |
| spellingShingle | Samjhana Kapali Anil Pokhrel Anup Bastola Reshma Tuladhar Dev Raj Joshi Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal Future Science OA mecA MRSA multi-drug resistance PLHIV PVL Staphylococcus aureus |
| title | Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal |
| title_full | Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal |
| title_fullStr | Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal |
| title_full_unstemmed | Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal |
| title_short | Methicillin-resistant Staphylococcus aureus nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal |
| title_sort | methicillin resistant staphylococcus aureus nasal colonization in people living with hiv and healthy people in kathmandu nepal |
| topic | mecA MRSA multi-drug resistance PLHIV PVL Staphylococcus aureus |
| url | https://www.future-science.com/doi/10.2144/fsoa-2021-0103 |
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