Corticomuscular coherence existed at the single motor unit level
The monosynaptic cortico-motoneuronal connections suggest the possibility of individual motor units (MUs) receiving independent commands from motor cortex. However, previous studies that used corticomuscular coherence (CMC) between electroencephalogram (EEG) signals and electromyogram (EMG) signals...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811924004968 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841545967468281856 |
|---|---|
| author | Yang Zheng Bofang Zheng Wei Qiang Yu Peng Guanghua Xu Gang Wang Lili Li Henry Shin |
| author_facet | Yang Zheng Bofang Zheng Wei Qiang Yu Peng Guanghua Xu Gang Wang Lili Li Henry Shin |
| author_sort | Yang Zheng |
| collection | DOAJ |
| description | The monosynaptic cortico-motoneuronal connections suggest the possibility of individual motor units (MUs) receiving independent commands from motor cortex. However, previous studies that used corticomuscular coherence (CMC) between electroencephalogram (EEG) signals and electromyogram (EMG) signals have not directly explored the corticospinal functionality at the single motoneuron level. The objective of this study is to find out whether synchronous activities exist between the motor cortex and individual MUs. Corticomuscular coherence was calculated between the EEG signals and the MU firing event trains which were extracted using the EMG decomposition technique. The results showed that some but not all MUs indeed had significant coherent activities with the contralateral motor cortex, which we named the cortico-motoneuronal coherence (CMnC). In contrast to the CMC only occurring in β and γ bands, CMnC occurred across the four common EEG frequency bands (θ, α, β and γ). Further, we identified individual MUs that showed significant interactions with the motor cortex. These coherent MUs (CohMU) could still be found even when the EMG signals were not coupled with the cortical activities. Compared with conventional CMC, our preliminary results indicated that the CMnC could potentially help to investigate the complex coupling between cortical and muscular activities due to its ability to separate different correlated components. This study proves that corticomuscular coherence exists at a single MU level, which provides a new perspective for the research on corticomuscular coupling. Further study on the CMnC could help deepen our understanding of the neural control of movement. |
| format | Article |
| id | doaj-art-3776258310c645a4a59dfe4f1742539a |
| institution | Kabale University |
| issn | 1095-9572 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj-art-3776258310c645a4a59dfe4f1742539a2025-01-11T06:38:36ZengElsevierNeuroImage1095-95722025-01-01305120999Corticomuscular coherence existed at the single motor unit levelYang Zheng0Bofang Zheng1Wei Qiang2Yu Peng3Guanghua Xu4Gang Wang5Lili Li6Henry Shin7Institute of Engineering and Medicine Interdisciplinary Studies and the State Key Laboratory for Manufacturing Systems Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, China; Corresponding authors.Institute of Engineering and Medicine Interdisciplinary Studies and the State Key Laboratory for Manufacturing Systems Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, ChinaInstitute of Engineering and Medicine Interdisciplinary Studies and the State Key Laboratory for Manufacturing Systems Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, ChinaDepartment of Rehabilitation, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, ChinaInstitute of Engineering and Medicine Interdisciplinary Studies and the State Key Laboratory for Manufacturing Systems Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, ChinaKey Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, ChinaCollege of Heath Science and Environment Engineering, Shenzhen Technology University, Shenzhen, Guangdong, ChinaSchool of Rehabilitation Sciences and Engineering, University of Health and Rehabilitation Sciences, Qingdao, Shandong, China; Corresponding authors.The monosynaptic cortico-motoneuronal connections suggest the possibility of individual motor units (MUs) receiving independent commands from motor cortex. However, previous studies that used corticomuscular coherence (CMC) between electroencephalogram (EEG) signals and electromyogram (EMG) signals have not directly explored the corticospinal functionality at the single motoneuron level. The objective of this study is to find out whether synchronous activities exist between the motor cortex and individual MUs. Corticomuscular coherence was calculated between the EEG signals and the MU firing event trains which were extracted using the EMG decomposition technique. The results showed that some but not all MUs indeed had significant coherent activities with the contralateral motor cortex, which we named the cortico-motoneuronal coherence (CMnC). In contrast to the CMC only occurring in β and γ bands, CMnC occurred across the four common EEG frequency bands (θ, α, β and γ). Further, we identified individual MUs that showed significant interactions with the motor cortex. These coherent MUs (CohMU) could still be found even when the EMG signals were not coupled with the cortical activities. Compared with conventional CMC, our preliminary results indicated that the CMnC could potentially help to investigate the complex coupling between cortical and muscular activities due to its ability to separate different correlated components. This study proves that corticomuscular coherence exists at a single MU level, which provides a new perspective for the research on corticomuscular coupling. Further study on the CMnC could help deepen our understanding of the neural control of movement.http://www.sciencedirect.com/science/article/pii/S1053811924004968Corticomuscular coherenceCortico-motoneuronal connectionsMonosynaptic projectionFiring event trains |
| spellingShingle | Yang Zheng Bofang Zheng Wei Qiang Yu Peng Guanghua Xu Gang Wang Lili Li Henry Shin Corticomuscular coherence existed at the single motor unit level NeuroImage Corticomuscular coherence Cortico-motoneuronal connections Monosynaptic projection Firing event trains |
| title | Corticomuscular coherence existed at the single motor unit level |
| title_full | Corticomuscular coherence existed at the single motor unit level |
| title_fullStr | Corticomuscular coherence existed at the single motor unit level |
| title_full_unstemmed | Corticomuscular coherence existed at the single motor unit level |
| title_short | Corticomuscular coherence existed at the single motor unit level |
| title_sort | corticomuscular coherence existed at the single motor unit level |
| topic | Corticomuscular coherence Cortico-motoneuronal connections Monosynaptic projection Firing event trains |
| url | http://www.sciencedirect.com/science/article/pii/S1053811924004968 |
| work_keys_str_mv | AT yangzheng corticomuscularcoherenceexistedatthesinglemotorunitlevel AT bofangzheng corticomuscularcoherenceexistedatthesinglemotorunitlevel AT weiqiang corticomuscularcoherenceexistedatthesinglemotorunitlevel AT yupeng corticomuscularcoherenceexistedatthesinglemotorunitlevel AT guanghuaxu corticomuscularcoherenceexistedatthesinglemotorunitlevel AT gangwang corticomuscularcoherenceexistedatthesinglemotorunitlevel AT lilili corticomuscularcoherenceexistedatthesinglemotorunitlevel AT henryshin corticomuscularcoherenceexistedatthesinglemotorunitlevel |