Mechanisms of the effect of gut microbes on depression through the microbiota-gut-brain axis

Mechanisms of the effect of gut microbes on depression through the microbiota-gut-brain axis

Depression is a significant public health issue which exerts profound psychological and social impacts on both individuals and society. However, existing therapeutic strategies often exhibit limited efficacy. Accumulating evidence underscores the vital role of gut microbiota in the pathophysiology o...

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Bibliographic Details
Main Authors: Xiangyan Zhou, Sixing Wang, Xiaohui Wang, Xinran Chen, Pei Zhou, Kai Ma, Peng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Nutrition
Subjects:
gut microbiota
MGB axis
depression
metabolism
neurotransmitters
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1634548/full
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