Substituted-Amidine Functionalized Monocyclic β-Lactams: Synthesis and In Vitro Antibacterial Profile
Background. Owing to the intrinsic stability against common β-lactamases and metallo-lactamases, monobactams gathered special attention in antibiotic drug development. However, so far, aztreonam is the only monobactam approved by FDA for clinical use. We designed new derivatives of aztreonam to enha...
Saved in:
| Main Authors: | Lili He, Lijuan Zhai, Jian Sun, Jingwen Ji, Jinbo Ji, Yuanbai Liu, Yangxiu Mu, Yuanyu Gao, Dong Tang, Rui Jiang, Ko Ko Myo, Zaw Min Thu, Haikang Yang, Zafar Iqbal, Zhixiang Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2021/9955206 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein(s)
by: Grabrijan Katarina, et al.
Published: (2024-09-01) -
Synthesis, characterization, and biological activity using computational study of synthesized monocyclic β-lactam ligands
by: Shweta Shweta, et al.
Published: (2025-06-01) -
Synthesis and Reactivity of Ynamine Amidines
by: B. Caillaux, et al.
Published: (1976-08-01) -
Fatty Amidine as Copper Corrosion Inhibitor
by: Zainal Alim Mas’ud, et al.
Published: (2020-01-01) -
Amidine Sulfonamides and Benzene Sulfonamides: Synthesis and Their Biological Evaluation
by: Muhammad Abdul Qadir, et al.
Published: (2015-01-01)