Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment

Objective. This study aimed to investigate if the presence of Modic changes (MCs) was correlated with lower back pain (LBP) and LBP-related disability in patients who underwent nonsurgical treatment. Methods. In this study, 129 patients who experienced consecutive LBP and underwent lumbar spine magn...

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Main Authors: Yufeng Chen, Huilin Yang, Lianfang Zhang, Yue Wang, Jun Zou
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2019/8185316
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author Yufeng Chen
Huilin Yang
Lianfang Zhang
Yue Wang
Jun Zou
author_facet Yufeng Chen
Huilin Yang
Lianfang Zhang
Yue Wang
Jun Zou
author_sort Yufeng Chen
collection DOAJ
description Objective. This study aimed to investigate if the presence of Modic changes (MCs) was correlated with lower back pain (LBP) and LBP-related disability in patients who underwent nonsurgical treatment. Methods. In this study, 129 patients who experienced consecutive LBP and underwent lumbar spine magnetic resonance imaging in our institute were divided into three groups according to the presence or type of MCs. The Oswestry Disability Index (ODI) and visual analog scale (VAS) were used to assess the outcomes of the treatment. Results. Based on the achieved results, there was no significant difference between three groups before treatment (P>0.05). Three months after undergoing nonsurgical treatment, the rates of improved ODI and VAS scores were statistically significantly different (P=0.014,  0.023). After an additional 3 months of treatment, in patients with Modic type I changes, the symptoms significantly improved in comparison with those 3 months prior (P=0.037,  0.026), while that improvement did not occur in patients with Modic type II changes (P>0.05). Conclusions. The existence of MCs affects the outcomes of nonsurgical treatment in patients with LBP. However, symptoms can be improved after an additional round of treatment for Modic type I changes, while this is not confirmed for Modic type II changes.
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institution Kabale University
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language English
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series Pain Research and Management
spelling doaj-art-37404866d7a7428f8ec2d66071f0e9742025-02-03T01:11:31ZengWileyPain Research and Management1203-67651918-15232019-01-01201910.1155/2019/81853168185316Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative TreatmentYufeng Chen0Huilin Yang1Lianfang Zhang2Yue Wang3Jun Zou4Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, ChinaDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, ChinaDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, ChinaDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310003, ChinaDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, ChinaObjective. This study aimed to investigate if the presence of Modic changes (MCs) was correlated with lower back pain (LBP) and LBP-related disability in patients who underwent nonsurgical treatment. Methods. In this study, 129 patients who experienced consecutive LBP and underwent lumbar spine magnetic resonance imaging in our institute were divided into three groups according to the presence or type of MCs. The Oswestry Disability Index (ODI) and visual analog scale (VAS) were used to assess the outcomes of the treatment. Results. Based on the achieved results, there was no significant difference between three groups before treatment (P>0.05). Three months after undergoing nonsurgical treatment, the rates of improved ODI and VAS scores were statistically significantly different (P=0.014,  0.023). After an additional 3 months of treatment, in patients with Modic type I changes, the symptoms significantly improved in comparison with those 3 months prior (P=0.037,  0.026), while that improvement did not occur in patients with Modic type II changes (P>0.05). Conclusions. The existence of MCs affects the outcomes of nonsurgical treatment in patients with LBP. However, symptoms can be improved after an additional round of treatment for Modic type I changes, while this is not confirmed for Modic type II changes.http://dx.doi.org/10.1155/2019/8185316
spellingShingle Yufeng Chen
Huilin Yang
Lianfang Zhang
Yue Wang
Jun Zou
Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment
Pain Research and Management
title Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment
title_full Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment
title_fullStr Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment
title_full_unstemmed Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment
title_short Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment
title_sort analyzing the influence of modic changes on patients with lower back pain undergoing conservative treatment
url http://dx.doi.org/10.1155/2019/8185316
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