DNA Hypomethylation Underlies Epigenetic Swapping between <i>AGO1</i> and <i>AGO1-V2</i> Isoforms in Tumors

DNA Hypomethylation Underlies Epigenetic Swapping between <i>AGO1</i> and <i>AGO1-V2</i> Isoforms in Tumors

Human tumors progress in part by accumulating epigenetic alterations, which include gains and losses of DNA methylation in different parts of the cancer cell genome. Recent work has revealed a link between these two opposite alterations by showing that DNA hypomethylation in tumors can induce the ex...

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Bibliographic Details
Main Authors: Jean S. Fain, Camille Wangermez, Axelle Loriot, Claudia Denoue, Charles De Smet
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Epigenomes
Subjects:
DNA methylation
cancer epigenetics
cancer-germline gene
Argonaute protein
Online Access:https://www.mdpi.com/2075-4655/8/3/24
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