Genome‐wide profiling of N6‐methyladenosine‐modified pseudogene‐derived long noncoding RNAs reveals the tumour‐promoting and innate immune‐restraining function of RPS15AP12 in ovarian cancer

Genome‐wide profiling of N6‐methyladenosine‐modified pseudogene‐derived long noncoding RNAs reveals the tumour‐promoting and innate immune‐restraining function of RPS15AP12 in ovarian cancer

Abstract Background Pseudogene‐derived lncRNAs are widely dysregulated in cancer. Technological advancements have facilitated the functional characterization of increasing pseudogenes in cancer progression. However, the association between pseudogenes and RNA N6‐methyladenosine (m6A) modification in...

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Main Authors: Jie Xu, Yifei Ren, Jiayi Lu, Fengjiang Qin, Dan Yang, Chunyan Tang, Yu Yang, Jing Xu, Tao Liu, Ping Yi
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Clinical and Translational Medicine
Subjects:
innate immune response
m6A
miRNA sponge
ovarian cancer
pseudogene
Online Access:https://doi.org/10.1002/ctm2.70249
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