Whole-genome sequencing characterisation of a new KPC-245 variant-carrying Klebsiella pneumoniae strain isolated from a transplanted patient and resistant to ceftazidime/avibactam, meropenem/vaborbactam and imipenem/relebactam

Whole-genome sequencing characterisation of a new KPC-245 variant-carrying Klebsiella pneumoniae strain isolated from a transplanted patient and resistant to ceftazidime/avibactam, meropenem/vaborbactam and imipenem/relebactam

ABSTRACT: Objective: In recent decades, the increasing prevalence of multidrug-resistant Klebsiella pneumoniae carbapenemase (KPC)-carrying K. pneumoniae (KPC-Kp) has become a worldwide public concern. Herein, we characterised a ceftazidime/avibactam (CAZ/AVI), meropenem/vaborbactam (MER/VAB) and i...

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Bibliographic Details
Main Authors: Claudia Vaiana, Roberta Vazzana, Salvatore Castelbuono, Andrea Cona, Alessandra Mularoni, Rita Minucci, Francesco Monaco, Daniele Di Carlo, Pier Giulio Conaldi, Alessia Gallo, Nicola Cuscino
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
K. pneumoniae
Carbapenemase
blaKPC variants
Ceftazidime-avibactam
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716525000657
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