Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review
Necrotizing soft tissue infections (NSTIs) are rare but life-threatening complications of colorectal cancer, often overlooked during patient diagnosis and treatment. NSTIs progress rapidly, leading to significant tissue damage and elevated mortality rates. This report presents the case of a 71-year-...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250925000228 |
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| author | Xin Xiang Jian Zheng Cheng-Wei Ma Lei Ruan Jing-Zheng Zhuang Qing-Chun Li |
| author_facet | Xin Xiang Jian Zheng Cheng-Wei Ma Lei Ruan Jing-Zheng Zhuang Qing-Chun Li |
| author_sort | Xin Xiang |
| collection | DOAJ |
| description | Necrotizing soft tissue infections (NSTIs) are rare but life-threatening complications of colorectal cancer, often overlooked during patient diagnosis and treatment. NSTIs progress rapidly, leading to significant tissue damage and elevated mortality rates. This report presents the case of a 71-year-old male who presented with abdominal pain and distention, later diagnosed with perforated colon cancer and NSTI of the left abdominal wall. Following admission, the patient developed septic shock and acute kidney injury. Emergency surgery was performed, including radical resection of the colon cancer, proximal colostomy, and extensive debridement of necrotic tissue. Postoperatively, Continuous Renal Replacement Therapy (CRRT) was used alongside standard treatments, contributing to a relatively rapid recovery. At the 30-month follow-up, no evidence of tumor recurrence was observed. |
| format | Article |
| id | doaj-art-3736013be95342df8ebef5f0bcac0577 |
| institution | Kabale University |
| issn | 2214-2509 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj-art-3736013be95342df8ebef5f0bcac05772025-01-31T05:11:19ZengElsevierIDCases2214-25092025-01-0139e02167Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature reviewXin Xiang0Jian Zheng1Cheng-Wei Ma2Lei Ruan3Jing-Zheng Zhuang4Qing-Chun Li5Department of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaCorrespondence to: No.126, Xiantai Street, Changchun, Jilin 130033, China.; Department of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, ChinaNecrotizing soft tissue infections (NSTIs) are rare but life-threatening complications of colorectal cancer, often overlooked during patient diagnosis and treatment. NSTIs progress rapidly, leading to significant tissue damage and elevated mortality rates. This report presents the case of a 71-year-old male who presented with abdominal pain and distention, later diagnosed with perforated colon cancer and NSTI of the left abdominal wall. Following admission, the patient developed septic shock and acute kidney injury. Emergency surgery was performed, including radical resection of the colon cancer, proximal colostomy, and extensive debridement of necrotic tissue. Postoperatively, Continuous Renal Replacement Therapy (CRRT) was used alongside standard treatments, contributing to a relatively rapid recovery. At the 30-month follow-up, no evidence of tumor recurrence was observed.http://www.sciencedirect.com/science/article/pii/S2214250925000228Colorectal cancerIntestinal perforationNecrotizing soft tissue infectionContinuous renal replacement therapy (CRRT) |
| spellingShingle | Xin Xiang Jian Zheng Cheng-Wei Ma Lei Ruan Jing-Zheng Zhuang Qing-Chun Li Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review IDCases Colorectal cancer Intestinal perforation Necrotizing soft tissue infection Continuous renal replacement therapy (CRRT) |
| title | Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review |
| title_full | Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review |
| title_fullStr | Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review |
| title_full_unstemmed | Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review |
| title_short | Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review |
| title_sort | perforated colon cancer complicated by necrotizing soft tissue infection a case report and literature review |
| topic | Colorectal cancer Intestinal perforation Necrotizing soft tissue infection Continuous renal replacement therapy (CRRT) |
| url | http://www.sciencedirect.com/science/article/pii/S2214250925000228 |
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