Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT in desert mice with steatosis
Background and aims: Fatty liver is one of the increasing diseases. Since changes in the gut microbiome causes fatty liver, taking probiotics may help to maintain gut microbial balance. This study was aimed to investigate the effect of probiotics consumption along with high intensity interval traini...
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Iran Air Force Health Administration
2023-10-01
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| Series: | فصلنامه ابن سینا |
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| Online Access: | http://ebnesina.ajaums.ac.ir/article-1-1273-en.pdf |
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| author | Saeed Shahmohammadi Farshad Ghazalian Hossein Shirvani Hossein Abednatanzi |
| author_facet | Saeed Shahmohammadi Farshad Ghazalian Hossein Shirvani Hossein Abednatanzi |
| author_sort | Saeed Shahmohammadi |
| collection | DOAJ |
| description | Background and aims: Fatty liver is one of the increasing diseases. Since changes in the gut microbiome causes fatty liver, taking probiotics may help to maintain gut microbial balance. This study was aimed to investigate the effect of probiotics consumption along with high intensity interval training (HIIT) on the ratio of liver enzymes (AST/ALT) in rats with steatosis.
Methods: In this experimental study, 40 male rats with an average weight of 200 to 250 grams were randomly divided into 5 groups of 8 (including healthy control, steatosis, HIIT+steatosis, probiotic+steatosis, HIIT+ probiotic+steatosis). They received high-fat emulsion (10 mg/kg/day) to induce steatosis. The probiotic consumption groups received 109 colonies/ml of Lactobacillus rhamnosus bacteria by gavage daily for 5 weeks and 5 days a week. The ratio of AST/ALT in the groups was compared.
Results:. The ratio of AST/ALT in the steatosis group was higher than the healthy control group. However, this ratio in steatosis+exercise+probiotic group compared to the steatosis group had the highest decrease than the other intervention groups which shows the positive effect of probiotic consumption and HIIT on improving rats with steatosis (p=0.001).
Conclusion: Lactobacillus rhamnosus probiotics foods consumption along with HIIT led to reduce the ratio of liver enzymes in mice with steatosis. |
| format | Article |
| id | doaj-art-372f9c2e26dc47cc88913dd9086291b3 |
| institution | DOAJ |
| issn | 1735-9503 2645-4653 |
| language | fas |
| publishDate | 2023-10-01 |
| publisher | Iran Air Force Health Administration |
| record_format | Article |
| series | فصلنامه ابن سینا |
| spelling | doaj-art-372f9c2e26dc47cc88913dd9086291b32025-08-20T03:00:57ZfasIran Air Force Health Administrationفصلنامه ابن سینا1735-95032645-46532023-10-012533343Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT in desert mice with steatosisSaeed Shahmohammadi0Farshad Ghazalian1Hossein Shirvani2Hossein Abednatanzi3 Department of Physical education, Science and Research Branch, Islamic Azad University, Tehran, Iran Department of Physical education, Science and Research Branch, Islamic Azad University, Tehran, Iran Sports Physiology Research Center, Lifestyle Research Institute, Baqiatallah University of Medical Sciences, Tehran, Iran Department of Physical education, Science and Research Branch, Islamic Azad University, Tehran, Iran Background and aims: Fatty liver is one of the increasing diseases. Since changes in the gut microbiome causes fatty liver, taking probiotics may help to maintain gut microbial balance. This study was aimed to investigate the effect of probiotics consumption along with high intensity interval training (HIIT) on the ratio of liver enzymes (AST/ALT) in rats with steatosis. Methods: In this experimental study, 40 male rats with an average weight of 200 to 250 grams were randomly divided into 5 groups of 8 (including healthy control, steatosis, HIIT+steatosis, probiotic+steatosis, HIIT+ probiotic+steatosis). They received high-fat emulsion (10 mg/kg/day) to induce steatosis. The probiotic consumption groups received 109 colonies/ml of Lactobacillus rhamnosus bacteria by gavage daily for 5 weeks and 5 days a week. The ratio of AST/ALT in the groups was compared. Results:. The ratio of AST/ALT in the steatosis group was higher than the healthy control group. However, this ratio in steatosis+exercise+probiotic group compared to the steatosis group had the highest decrease than the other intervention groups which shows the positive effect of probiotic consumption and HIIT on improving rats with steatosis (p=0.001). Conclusion: Lactobacillus rhamnosus probiotics foods consumption along with HIIT led to reduce the ratio of liver enzymes in mice with steatosis.http://ebnesina.ajaums.ac.ir/article-1-1273-en.pdf: lactobacillus ggexercise trainingnonalcoholic fatty liver diseaseprobiotic |
| spellingShingle | Saeed Shahmohammadi Farshad Ghazalian Hossein Shirvani Hossein Abednatanzi Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT in desert mice with steatosis فصلنامه ابن سینا : lactobacillus gg exercise training nonalcoholic fatty liver disease probiotic |
| title | Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT
in desert mice with steatosis |
| title_full | Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT
in desert mice with steatosis |
| title_fullStr | Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT
in desert mice with steatosis |
| title_full_unstemmed | Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT
in desert mice with steatosis |
| title_short | Effect of Lactobacillus ramensus probiotic use and High Intensity Interval Training on the ratio of liver enzymes AST/ALT
in desert mice with steatosis |
| title_sort | effect of lactobacillus ramensus probiotic use and high intensity interval training on the ratio of liver enzymes ast alt in desert mice with steatosis |
| topic | : lactobacillus gg exercise training nonalcoholic fatty liver disease probiotic |
| url | http://ebnesina.ajaums.ac.ir/article-1-1273-en.pdf |
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