Noninvasive Monitoring of Pneumococcal Meningitis and Evaluation of Treatment Efficacy in an Experimental Mouse Model
Noninvasive real-time in vivo bioluminescent imaging was used to assess the spread of Streptococcus pneumoniae throughout the spinal cord and brain during the acute stages of bacterial meningitis. A mouse model was established by lumbar (LP) or intracisternal (IC) injection of bioluminescent S. pneu...
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Main Authors: | Jagath L. Kadurugamuwa, Kshitij Modi, Jun Yu, Kevin P. Francis, Carlos Orihuela, Elaine Tuomanen, Anthony F. Purchio, Pamela R. Contag |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2005-04-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.1162/15353500200505106 |
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