Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report

Recurrent benign lymphocytic meningitis (RBLM) is an uncommon form of aseptic meningitis characterized by the recurrence of meningeal symptoms followed by spontaneous recovery. Historically, RBLM has been attributed to herpes simplex virus (HSV) type 2 infection. Diagnosis is traditionally confirmed...

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Main Authors: Sirine Ahmad, Mohammed Alsaeed
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-10-01
Series:Dr. Sulaiman Al Habib Medical Journal
Subjects:
Online Access:https://journals.lww.com/10.1007/s44229-023-00036-z
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author Sirine Ahmad
Mohammed Alsaeed
author_facet Sirine Ahmad
Mohammed Alsaeed
author_sort Sirine Ahmad
collection DOAJ
description Recurrent benign lymphocytic meningitis (RBLM) is an uncommon form of aseptic meningitis characterized by the recurrence of meningeal symptoms followed by spontaneous recovery. Historically, RBLM has been attributed to herpes simplex virus (HSV) type 2 infection. Diagnosis is traditionally confirmed by PCR of viral DNA isolated from the CSF. Although the disease course is usually benign, antiviral therapy may benefit some patients. Here, we report the case of a young woman diagnosed with four episodes of aseptic meningitis within 10 years. The presence of HSV type 2 in the CSF was confirmed using PCR in three of the episodes. After the resolution of acute attacks, the patient was symptom-free with no neurological sequelae.
format Article
id doaj-art-37294de2c8374f57b1cdac7f3ed6b358
institution Kabale University
issn 2666-819X
2590-3349
language English
publishDate 2023-10-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Dr. Sulaiman Al Habib Medical Journal
spelling doaj-art-37294de2c8374f57b1cdac7f3ed6b3582025-08-20T03:41:43ZengWolters Kluwer Medknow PublicationsDr. Sulaiman Al Habib Medical Journal2666-819X2590-33492023-10-015415916110.1007/s44229-023-00036-zRecurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case ReportSirine AhmadMohammed AlsaeedRecurrent benign lymphocytic meningitis (RBLM) is an uncommon form of aseptic meningitis characterized by the recurrence of meningeal symptoms followed by spontaneous recovery. Historically, RBLM has been attributed to herpes simplex virus (HSV) type 2 infection. Diagnosis is traditionally confirmed by PCR of viral DNA isolated from the CSF. Although the disease course is usually benign, antiviral therapy may benefit some patients. Here, we report the case of a young woman diagnosed with four episodes of aseptic meningitis within 10 years. The presence of HSV type 2 in the CSF was confirmed using PCR in three of the episodes. After the resolution of acute attacks, the patient was symptom-free with no neurological sequelae.https://journals.lww.com/10.1007/s44229-023-00036-zrecurrent meningitisrecurrent benign lymphocytic meningitishsv-2
spellingShingle Sirine Ahmad
Mohammed Alsaeed
Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report
Dr. Sulaiman Al Habib Medical Journal
recurrent meningitis
recurrent benign lymphocytic meningitis
hsv-2
title Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report
title_full Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report
title_fullStr Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report
title_full_unstemmed Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report
title_short Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report
title_sort recurrent benign lymphocytic meningitis due to hsv 2 a case report
topic recurrent meningitis
recurrent benign lymphocytic meningitis
hsv-2
url https://journals.lww.com/10.1007/s44229-023-00036-z
work_keys_str_mv AT sirineahmad recurrentbenignlymphocyticmeningitisduetohsv2acasereport
AT mohammedalsaeed recurrentbenignlymphocyticmeningitisduetohsv2acasereport