A tumor-microvessel on-a-chip reveals a mechanism for cancer cell cluster intravasation

A tumor-microvessel on-a-chip reveals a mechanism for cancer cell cluster intravasation

Summary: Circulating tumor cell (CTC) clusters are often detected in blood samples of patients with high-grade tumor and are associated with tumor metastasis and poor prognosis. However, the underlying mechanisms by which cancer cell clusters are released from primary tumors beyond blood vessel barr...

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Main Authors: Yukinori Ikeda, Makoto Kondo, Jun-ichi Suehiro, Hiroko Oshima, Sau Yee Kok, Kazuki Takahashi, Joris Pauty, Dong Wang, Hiroyuki Sakurai, Tetsuro Watabe, Masanobu Oshima, Yukiko T. Matsunaga
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
Subjects:
Microenvironment
Biological sciences
Biotechnology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225007783
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http://www.sciencedirect.com/science/article/pii/S2589004225007783

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