Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule Summary
Background: Current actinic keratosis (AK) treatment guidelines are controversial and incomplete, leaving an unmet need for clearer and more in-depth guidance on the usage of photodynamic therapy (PDT) in AKs. Objective: To gain consensus on the use of PDT for AKs using a modified Delphi method. Met...
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Elsevier
2025-06-01
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| Series: | JAAD International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666328725000227 |
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| author | Vishal A. Patel, MD Sarah T. Arron, MD Brian Berman, MD, PhD M. Shane Chapman, MD, MBA Anokhi Jambusaria-Pahlajani, MD George Martin, MD Anthony M. Rossi, MD Todd Schlesinger, MD Nathalie C. Zeitouni, MDCM Neal Bhatia, MD |
| author_facet | Vishal A. Patel, MD Sarah T. Arron, MD Brian Berman, MD, PhD M. Shane Chapman, MD, MBA Anokhi Jambusaria-Pahlajani, MD George Martin, MD Anthony M. Rossi, MD Todd Schlesinger, MD Nathalie C. Zeitouni, MDCM Neal Bhatia, MD |
| author_sort | Vishal A. Patel, MD |
| collection | DOAJ |
| description | Background: Current actinic keratosis (AK) treatment guidelines are controversial and incomplete, leaving an unmet need for clearer and more in-depth guidance on the usage of photodynamic therapy (PDT) in AKs. Objective: To gain consensus on the use of PDT for AKs using a modified Delphi method. Methods: Consensus statements were developed after a literature review of topics surrounding PDT and AKs. Ten panelists voted through electronic questionnaires rating each statement on a three-point Likert-type scale: strongly agree, agree, and disagree. Consensus was established when ≥70% of panelists strongly agreed on the statement. Statements that did not meet the threshold were revised after each round of voting and sent out for the next round of voting. A virtual meeting was held after 2 rounds of voting to discuss outstanding statements. Results: Three modified Delphi rounds were completed in total and 1 virtual meeting was held. All 10 experts responded to all rounds of voting. A total of 55 statements established consensus with the ≥70% majority requirement necessary. Limitations: Recommendations are based on expert opinions. Conclusion: The results from this consensus panel are intended to bridge gaps in the existing guidelines and will continue to evolve. |
| format | Article |
| id | doaj-art-3707d90ab18f4bdc96f2c8d9f4f26ed9 |
| institution | DOAJ |
| issn | 2666-3287 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JAAD International |
| spelling | doaj-art-3707d90ab18f4bdc96f2c8d9f4f26ed92025-08-20T03:09:57ZengElsevierJAAD International2666-32872025-06-0120627310.1016/j.jdin.2024.11.011Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule SummaryVishal A. Patel, MD0Sarah T. Arron, MD1Brian Berman, MD, PhD2M. Shane Chapman, MD, MBA3Anokhi Jambusaria-Pahlajani, MD4George Martin, MD5Anthony M. Rossi, MD6Todd Schlesinger, MD7Nathalie C. Zeitouni, MDCM8Neal Bhatia, MD9Department of Dermatology, George Washington University School of Medicine & Health Sciences, Washington, District of ColumbiaPeninsula Dermatology, Burlingame, CaliforniaUniversity of Miami Miller School of Medicine, Miami, Florida; Center for Clinical and Cosmetic Research, Aventura, FloridaDepartment of Dermatology, Dartmouth Hitchcock Medical Center, Nashua, New Hampshire; Geisel School of Medicine at Dartmouth, Lebanon and Hanover, New HampshireDivision of Dermatology, Department of Internal Medicine, The University of Texas at Austin Dell Medical School, Austin, TexasDr. George Martin Dermatology Associates, Kihei, HawaiiMemorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York; New York Presbyterian Hospital, New York, New YorkClinical Research Center of the Carolinas, Charleston, South CarolinaMedical Dermatology Specialists, Phoenix, Arizona; University of Arizona COM, Phoenix, ArizonaTherapeutics Clinical Research, San Diego, California; Correspondence to: Dr Neal Bhatia, MD, Therapeutics Clinical Research, 9025 Balboa Ave, Suite 105, San Diego, CA 92123.Background: Current actinic keratosis (AK) treatment guidelines are controversial and incomplete, leaving an unmet need for clearer and more in-depth guidance on the usage of photodynamic therapy (PDT) in AKs. Objective: To gain consensus on the use of PDT for AKs using a modified Delphi method. Methods: Consensus statements were developed after a literature review of topics surrounding PDT and AKs. Ten panelists voted through electronic questionnaires rating each statement on a three-point Likert-type scale: strongly agree, agree, and disagree. Consensus was established when ≥70% of panelists strongly agreed on the statement. Statements that did not meet the threshold were revised after each round of voting and sent out for the next round of voting. A virtual meeting was held after 2 rounds of voting to discuss outstanding statements. Results: Three modified Delphi rounds were completed in total and 1 virtual meeting was held. All 10 experts responded to all rounds of voting. A total of 55 statements established consensus with the ≥70% majority requirement necessary. Limitations: Recommendations are based on expert opinions. Conclusion: The results from this consensus panel are intended to bridge gaps in the existing guidelines and will continue to evolve.http://www.sciencedirect.com/science/article/pii/S2666328725000227actinic keratosisaminolevulinic acid (ALA)basal cell carcinoma (BCC)cutaneous squamous cell carcinoma (cSCC)field therapyorgan transplant recipients |
| spellingShingle | Vishal A. Patel, MD Sarah T. Arron, MD Brian Berman, MD, PhD M. Shane Chapman, MD, MBA Anokhi Jambusaria-Pahlajani, MD George Martin, MD Anthony M. Rossi, MD Todd Schlesinger, MD Nathalie C. Zeitouni, MDCM Neal Bhatia, MD Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule Summary JAAD International actinic keratosis aminolevulinic acid (ALA) basal cell carcinoma (BCC) cutaneous squamous cell carcinoma (cSCC) field therapy organ transplant recipients |
| title | Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule Summary |
| title_full | Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule Summary |
| title_fullStr | Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule Summary |
| title_full_unstemmed | Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule Summary |
| title_short | Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patientsCapsule Summary |
| title_sort | expert consensus based recommendations on the use of photodynamic therapy in actinic keratosis patientscapsule summary |
| topic | actinic keratosis aminolevulinic acid (ALA) basal cell carcinoma (BCC) cutaneous squamous cell carcinoma (cSCC) field therapy organ transplant recipients |
| url | http://www.sciencedirect.com/science/article/pii/S2666328725000227 |
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