A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures

The fusion of biomaterial science with clinical practice in oculoplastic and orbital surgery, particularly in the reconstruction of the posterior lamella of the eyelid, the lacrimal system, orbital floor fractures, and the development of implants for anophthalmic sockets, represents a frontier where...

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Main Authors: Merve Kulbay, Kevin Y. Wu, Adam Hocini, Patrick Daigle
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2024-11-01
Series:Exploration of BioMat-X
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Online Access:https://www.explorationpub.com/uploads/Article/A101322/101322.pdf
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author Merve Kulbay
Kevin Y. Wu
Adam Hocini
Patrick Daigle
author_facet Merve Kulbay
Kevin Y. Wu
Adam Hocini
Patrick Daigle
author_sort Merve Kulbay
collection DOAJ
description The fusion of biomaterial science with clinical practice in oculoplastic and orbital surgery, particularly in the reconstruction of the posterior lamella of the eyelid, the lacrimal system, orbital floor fractures, and the development of implants for anophthalmic sockets, represents a frontier where materials meet surgical techniques. This review, which spans research from 2015 to 2023, delves into the application and integration of biopolymers and functional biomaterials in these complex areas. The discussion begins by reviewing the key anatomy of the external ocular surface, lacrimal system, and orbit. It then summarizes the various current surgical approaches for treating diseases affecting the external ocular surface and orbital involvement, with an emphasis on the associated challenges. The discussion continues with a comprehensive overview of the advantages and disadvantages of current and emerging biomaterials, including synthetic and natural polymers, used in reconstructive surgeries. These include applications for eyelid structure reconstruction, lacrimal system repair, orbital bone fracture repair, and orbital socket reconstruction. Throughout the review, the pathophysiology and challenges associated with these reconstructive procedures are explored, with an emphasis on surgical nuances and the ongoing pursuit of optimal reconstruction techniques. Finally, this review serves as a valuable resource for familiarizing clinicians with current knowledge and generating future hypotheses. It concludes that no evidence-based guidelines currently exist in oculoplastic surgery regarding the use of biopolymers in reconstructive procedures. Further research is needed to evaluate the efficacy and reproducibility of these biopolymers.
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spelling doaj-art-3700dcc72b2447e7a11b71bea2b7562e2025-08-20T03:51:19ZengOpen Exploration Publishing Inc.Exploration of BioMat-X2996-94762024-11-011630033010.37349/ebmx.2024.00022A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structuresMerve Kulbay0https://orcid.org/0000-0003-2756-3973Kevin Y. Wu1https://orcid.org/0000-0002-1662-6900Adam Hocini2https://orcid.org/0009-0004-4096-7037Patrick Daigle3https://orcid.org/0000-0001-8323-6761Department of Ophthalmology & Visual Sciences, McGill University, Montréal, QC H4A0A4, CanadaDivision of Ophthalmology, Department of Surgery, University of Sherbrooke, Sherbrooke, QC J1K2R1, CanadaFaculty of Medicine, Université de Montréal, Montréal, QC H3T1J4, CanadaDivision of Ophthalmology, Department of Surgery, University of Sherbrooke, Sherbrooke, QC J1K2R1, CanadaThe fusion of biomaterial science with clinical practice in oculoplastic and orbital surgery, particularly in the reconstruction of the posterior lamella of the eyelid, the lacrimal system, orbital floor fractures, and the development of implants for anophthalmic sockets, represents a frontier where materials meet surgical techniques. This review, which spans research from 2015 to 2023, delves into the application and integration of biopolymers and functional biomaterials in these complex areas. The discussion begins by reviewing the key anatomy of the external ocular surface, lacrimal system, and orbit. It then summarizes the various current surgical approaches for treating diseases affecting the external ocular surface and orbital involvement, with an emphasis on the associated challenges. The discussion continues with a comprehensive overview of the advantages and disadvantages of current and emerging biomaterials, including synthetic and natural polymers, used in reconstructive surgeries. These include applications for eyelid structure reconstruction, lacrimal system repair, orbital bone fracture repair, and orbital socket reconstruction. Throughout the review, the pathophysiology and challenges associated with these reconstructive procedures are explored, with an emphasis on surgical nuances and the ongoing pursuit of optimal reconstruction techniques. Finally, this review serves as a valuable resource for familiarizing clinicians with current knowledge and generating future hypotheses. It concludes that no evidence-based guidelines currently exist in oculoplastic surgery regarding the use of biopolymers in reconstructive procedures. Further research is needed to evaluate the efficacy and reproducibility of these biopolymers.https://www.explorationpub.com/uploads/Article/A101322/101322.pdfbiopolymersorbital implantseyelid surgerylacrimal system
spellingShingle Merve Kulbay
Kevin Y. Wu
Adam Hocini
Patrick Daigle
A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures
Exploration of BioMat-X
biopolymers
orbital implants
eyelid surgery
lacrimal system
title A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures
title_full A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures
title_fullStr A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures
title_full_unstemmed A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures
title_short A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures
title_sort review of biopolymer innovations in oculoplastic surgery reconstruction of eyelid lacrimal and orbital structures
topic biopolymers
orbital implants
eyelid surgery
lacrimal system
url https://www.explorationpub.com/uploads/Article/A101322/101322.pdf
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