Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series Study
Introduction: Children with Wilms tumor can rarely experience late relapse of disease. Sometimes bilateral nephrectomy is necessary; as a consequence, the patient needs hemodialysis while waiting for renal transplantation. The waiting time to transplantation after cancer has always been a...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2025-03-01
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| Series: | Case Reports in Oncology |
| Online Access: | https://karger.com/article/doi/10.1159/000543176 |
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| author | Teresa Battaglia Pietro Casartelli Monica Muraca Stefania Sorrentino Sabrina Zanardi Fiammetta Sertorio Gaetano Valerio Vellone Alberto Magnasco Alberto Garaventa Loredana Amoroso |
| author_facet | Teresa Battaglia Pietro Casartelli Monica Muraca Stefania Sorrentino Sabrina Zanardi Fiammetta Sertorio Gaetano Valerio Vellone Alberto Magnasco Alberto Garaventa Loredana Amoroso |
| author_sort | Teresa Battaglia |
| collection | DOAJ |
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Introduction: Children with Wilms tumor can rarely experience late relapse of disease. Sometimes bilateral nephrectomy is necessary; as a consequence, the patient needs hemodialysis while waiting for renal transplantation. The waiting time to transplantation after cancer has always been a debated issue. Case Presentation: We present 2 cases of late relapse of Wilms tumor who underwent bilateral nephrectomy. Patient 1 was put in the attending list for renal transplant after 5 years to stop treatment, attending the conventional time; however, she died before transplant because of complications in SARS-COVID-19 infection. Patient 2 underwent a renal transplant sooner compared to the conventional time, improving her quality of life and alive. Conclusion: If bilateral nephrectomy is necessary in oncological patients, the timing of renal transplant should be discussed by multidisciplinary team. In our cases, the different time to renal transplantation was associated with different outcomes. Clinicians should have common lines about the time of renal transplantation in pediatric oncology; however, a personalized planning could be suggested after discussion among specialists, evaluating case to case. The presented field needs more knowledge and further larger case series are necessary to evaluate outcome related to the timing of renal transplant; in this view, collaboration between oncology centers is strongly required. |
| format | Article |
| id | doaj-art-36fca5b7730f420dbc4e3ad4c4e7cbe1 |
| institution | OA Journals |
| issn | 1662-6575 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj-art-36fca5b7730f420dbc4e3ad4c4e7cbe12025-08-20T02:31:55ZengKarger PublishersCase Reports in Oncology1662-65752025-03-0118144945510.1159/000543176Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series StudyTeresa BattagliaPietro CasartelliMonica MuracaStefania SorrentinoSabrina ZanardiFiammetta SertorioGaetano Valerio VelloneAlberto MagnascoAlberto GaraventaLoredana Amoroso Introduction: Children with Wilms tumor can rarely experience late relapse of disease. Sometimes bilateral nephrectomy is necessary; as a consequence, the patient needs hemodialysis while waiting for renal transplantation. The waiting time to transplantation after cancer has always been a debated issue. Case Presentation: We present 2 cases of late relapse of Wilms tumor who underwent bilateral nephrectomy. Patient 1 was put in the attending list for renal transplant after 5 years to stop treatment, attending the conventional time; however, she died before transplant because of complications in SARS-COVID-19 infection. Patient 2 underwent a renal transplant sooner compared to the conventional time, improving her quality of life and alive. Conclusion: If bilateral nephrectomy is necessary in oncological patients, the timing of renal transplant should be discussed by multidisciplinary team. In our cases, the different time to renal transplantation was associated with different outcomes. Clinicians should have common lines about the time of renal transplantation in pediatric oncology; however, a personalized planning could be suggested after discussion among specialists, evaluating case to case. The presented field needs more knowledge and further larger case series are necessary to evaluate outcome related to the timing of renal transplant; in this view, collaboration between oncology centers is strongly required. https://karger.com/article/doi/10.1159/000543176 |
| spellingShingle | Teresa Battaglia Pietro Casartelli Monica Muraca Stefania Sorrentino Sabrina Zanardi Fiammetta Sertorio Gaetano Valerio Vellone Alberto Magnasco Alberto Garaventa Loredana Amoroso Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series Study Case Reports in Oncology |
| title | Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series Study |
| title_full | Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series Study |
| title_fullStr | Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series Study |
| title_full_unstemmed | Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series Study |
| title_short | Timing of Renal Transplant in Survivor Children with Relapse of Wilms Tumor: A Case Series Study |
| title_sort | timing of renal transplant in survivor children with relapse of wilms tumor a case series study |
| url | https://karger.com/article/doi/10.1159/000543176 |
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