Research progress on the formation and regulation of viable but nonculturable cells in biofilms
The formation and regulation of viable but nonculturable (VBNC) cells in biofilms is a cutting-edge topic in microbiology research. Although there has been controversy over the concept of the VBNC state in the past, its significant impact on ecological balance and public safety cannot be denied. The...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Zhejiang University Press
2024-08-01
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| Series: | 浙江大学学报. 农业与生命科学版 |
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| Online Access: | https://www.academax.com/doi/10.3785/j.issn.1008-9209.2023.10.181 |
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| _version_ | 1849419488676544512 |
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| author | XU Zhenbo ZHONG Feifeng ZHAO Xihong DENG Yang ZHAO Feng LIU Junyan |
| author_facet | XU Zhenbo ZHONG Feifeng ZHAO Xihong DENG Yang ZHAO Feng LIU Junyan |
| author_sort | XU Zhenbo |
| collection | DOAJ |
| description | The formation and regulation of viable but nonculturable (VBNC) cells in biofilms is a cutting-edge topic in microbiology research. Although there has been controversy over the concept of the VBNC state in the past, its significant impact on ecological balance and public safety cannot be denied. The formation of VBNC cells regulated by multiple factors has gradually been revealed, including pathways such as gene expression and protein synthesis. These studies lay the foundation for analyzing the survival strategies and ecological adaptability of VBNC cells. This review summarized VBNC cells from multiple perspectives, including the discussion of their definition, the presence of VBNC cells in biofilms, their formation triggers and relevant mechanisms, and the regulation and prevention of VBNC cells. The focus of future research will be to explore the function and significance of VBNC cells, intervene in their formation, solve related problems in innovative ways, and reveal the molecular mechanisms and metabolic pathways of VBNC cells in detail. |
| format | Article |
| id | doaj-art-36f55bab161140ae94f663e2b25b1c2b |
| institution | Kabale University |
| issn | 1008-9209 2097-5155 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Zhejiang University Press |
| record_format | Article |
| series | 浙江大学学报. 农业与生命科学版 |
| spelling | doaj-art-36f55bab161140ae94f663e2b25b1c2b2025-08-20T03:32:04ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552024-08-015056858310.3785/j.issn.1008-9209.2023.10.18110089209Research progress on the formation and regulation of viable but nonculturable cells in biofilmsXU ZhenboZHONG FeifengZHAO XihongDENG YangZHAO FengLIU JunyanThe formation and regulation of viable but nonculturable (VBNC) cells in biofilms is a cutting-edge topic in microbiology research. Although there has been controversy over the concept of the VBNC state in the past, its significant impact on ecological balance and public safety cannot be denied. The formation of VBNC cells regulated by multiple factors has gradually been revealed, including pathways such as gene expression and protein synthesis. These studies lay the foundation for analyzing the survival strategies and ecological adaptability of VBNC cells. This review summarized VBNC cells from multiple perspectives, including the discussion of their definition, the presence of VBNC cells in biofilms, their formation triggers and relevant mechanisms, and the regulation and prevention of VBNC cells. The focus of future research will be to explore the function and significance of VBNC cells, intervene in their formation, solve related problems in innovative ways, and reveal the molecular mechanisms and metabolic pathways of VBNC cells in detail.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2023.10.181viable but nonculturable cellsbiofilmregulatory mechanism |
| spellingShingle | XU Zhenbo ZHONG Feifeng ZHAO Xihong DENG Yang ZHAO Feng LIU Junyan Research progress on the formation and regulation of viable but nonculturable cells in biofilms 浙江大学学报. 农业与生命科学版 viable but nonculturable cells biofilm regulatory mechanism |
| title | Research progress on the formation and regulation of viable but nonculturable cells in biofilms |
| title_full | Research progress on the formation and regulation of viable but nonculturable cells in biofilms |
| title_fullStr | Research progress on the formation and regulation of viable but nonculturable cells in biofilms |
| title_full_unstemmed | Research progress on the formation and regulation of viable but nonculturable cells in biofilms |
| title_short | Research progress on the formation and regulation of viable but nonculturable cells in biofilms |
| title_sort | research progress on the formation and regulation of viable but nonculturable cells in biofilms |
| topic | viable but nonculturable cells biofilm regulatory mechanism |
| url | https://www.academax.com/doi/10.3785/j.issn.1008-9209.2023.10.181 |
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