Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment
Objective. This study aimed to compare the intranasal administration of midazolam and dexmedetomidine in uncooperative children with Down syndrome. Materials and Methods. The sample consisted of 20 children with Down syndrome aged 5 to 11 years who were divided equally into two groups: Group 1 (expe...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2022/7344928 |
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| _version_ | 1832551661320536064 |
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| author | Mohamad Nabil Hamod Chaza Kouchaji Faten Rostom Hasan Alzoubi Imad Katbeh Nikolay Tuturov |
| author_facet | Mohamad Nabil Hamod Chaza Kouchaji Faten Rostom Hasan Alzoubi Imad Katbeh Nikolay Tuturov |
| author_sort | Mohamad Nabil Hamod |
| collection | DOAJ |
| description | Objective. This study aimed to compare the intranasal administration of midazolam and dexmedetomidine in uncooperative children with Down syndrome. Materials and Methods. The sample consisted of 20 children with Down syndrome aged 5 to 11 years who were divided equally into two groups: Group 1 (experimental) nasal dexmedetomidine and Group 2 (control) nasal midazolam. The efficacy of both the drugs was evaluated according to Ohio State University Behavioral Rating Scale (OSUBRS), University of Michigan scale (UMSS), and Houpt general behavior scale. Results. Both substances have been effective in the management of children with Down syndrome. There were no statistically significant differences for Ohio State University Behavioral Rating Scale (OSUBRS) (P value = 0.631), University of Michigan scale (UMSS) (P value = 0.739), and Houpt general behavior scale (P value = 0.481). Conclusion. Both midazolam and dexmedetomidine nasal can be used to sedate children with Down syndrome. |
| format | Article |
| id | doaj-art-36f3a3ee8903488a88c8884f1ed37453 |
| institution | Kabale University |
| issn | 1687-8736 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-36f3a3ee8903488a88c8884f1ed374532025-02-03T06:00:56ZengWileyInternational Journal of Dentistry1687-87362022-01-01202210.1155/2022/7344928Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental TreatmentMohamad Nabil Hamod0Chaza Kouchaji1Faten Rostom2Hasan Alzoubi3Imad Katbeh4Nikolay Tuturov5Department of Pediatric DentistryDepartment of Pediatric DentistryDepartment of Anesthesia and ReanimationDepartment of Pediatric DentistryDepartment of Pediatric Dentistry and OrthodonticsDepartment of Pediatric Dentistry and OrthodonticsObjective. This study aimed to compare the intranasal administration of midazolam and dexmedetomidine in uncooperative children with Down syndrome. Materials and Methods. The sample consisted of 20 children with Down syndrome aged 5 to 11 years who were divided equally into two groups: Group 1 (experimental) nasal dexmedetomidine and Group 2 (control) nasal midazolam. The efficacy of both the drugs was evaluated according to Ohio State University Behavioral Rating Scale (OSUBRS), University of Michigan scale (UMSS), and Houpt general behavior scale. Results. Both substances have been effective in the management of children with Down syndrome. There were no statistically significant differences for Ohio State University Behavioral Rating Scale (OSUBRS) (P value = 0.631), University of Michigan scale (UMSS) (P value = 0.739), and Houpt general behavior scale (P value = 0.481). Conclusion. Both midazolam and dexmedetomidine nasal can be used to sedate children with Down syndrome.http://dx.doi.org/10.1155/2022/7344928 |
| spellingShingle | Mohamad Nabil Hamod Chaza Kouchaji Faten Rostom Hasan Alzoubi Imad Katbeh Nikolay Tuturov Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment International Journal of Dentistry |
| title | Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment |
| title_full | Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment |
| title_fullStr | Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment |
| title_full_unstemmed | Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment |
| title_short | Evaluation of the Efficacy of Nasal Sedation Midazolam Compared with Dexmedetomidine in the Management of Uncooperative Children with Down Syndrome during Dental Treatment |
| title_sort | evaluation of the efficacy of nasal sedation midazolam compared with dexmedetomidine in the management of uncooperative children with down syndrome during dental treatment |
| url | http://dx.doi.org/10.1155/2022/7344928 |
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