Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study
Aim: To evaluate the antimicrobial efficacy of different irrigants combined with silver nanoparticles. Materials and Methods: Thirty-five patients were divided into seven groups (two control and five experimental), including Group 1: negative control (normal saline), Group 2: positive control (sodiu...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_186_25 |
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| author | Ajay Chhabra Himani Mehra Priyanka Yadav K. P. Ramya Saravana B. Prathap Mallika Sengupta Sona J. Parvathy Vandana Chhabra |
| author_facet | Ajay Chhabra Himani Mehra Priyanka Yadav K. P. Ramya Saravana B. Prathap Mallika Sengupta Sona J. Parvathy Vandana Chhabra |
| author_sort | Ajay Chhabra |
| collection | DOAJ |
| description | Aim:
To evaluate the antimicrobial efficacy of different irrigants combined with silver nanoparticles.
Materials and Methods:
Thirty-five patients were divided into seven groups (two control and five experimental), including Group 1: negative control (normal saline), Group 2: positive control (sodium hypochlorite), and Group 3 (sodium hypochlorite + AgNP), Group 4 (Twin Kleen), Group 5 (Twin Kleen + AgNP), Group 6 (Q Mix), and Group 7 (Q Mix + AgNP). Pre- and post-treatment bacterial samples were collected for analysis.
Results:
Sodium hypochlorite combined with silver nanoparticles demonstrated the highest antimicrobial efficacy among the tested irrigants, with a significant difference confirmed by the Chi-square statistical analysis.
Conclusion:
Within the limitations of the study, it can be concluded that sodium hypochlorite when mixed with the silver nanoparticles showed higher antimicrobial efficacy as compared to the other tested groups. |
| format | Article |
| id | doaj-art-36ea032df16142a5b3b027e0de5b8cb0 |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-36ea032df16142a5b3b027e0de5b8cb02025-08-20T03:31:36ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-06-0117Suppl 2S1908S191010.4103/jpbs.jpbs_186_25Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo StudyAjay ChhabraHimani MehraPriyanka YadavK. P. RamyaSaravana B. PrathapMallika SenguptaSona J. ParvathyVandana ChhabraAim: To evaluate the antimicrobial efficacy of different irrigants combined with silver nanoparticles. Materials and Methods: Thirty-five patients were divided into seven groups (two control and five experimental), including Group 1: negative control (normal saline), Group 2: positive control (sodium hypochlorite), and Group 3 (sodium hypochlorite + AgNP), Group 4 (Twin Kleen), Group 5 (Twin Kleen + AgNP), Group 6 (Q Mix), and Group 7 (Q Mix + AgNP). Pre- and post-treatment bacterial samples were collected for analysis. Results: Sodium hypochlorite combined with silver nanoparticles demonstrated the highest antimicrobial efficacy among the tested irrigants, with a significant difference confirmed by the Chi-square statistical analysis. Conclusion: Within the limitations of the study, it can be concluded that sodium hypochlorite when mixed with the silver nanoparticles showed higher antimicrobial efficacy as compared to the other tested groups.https://journals.lww.com/10.4103/jpbs.jpbs_186_25antimicrobial efficacyq mixroot canal irrigantssilver nanoparticlessodium hypochloritetwin kleen |
| spellingShingle | Ajay Chhabra Himani Mehra Priyanka Yadav K. P. Ramya Saravana B. Prathap Mallika Sengupta Sona J. Parvathy Vandana Chhabra Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study Journal of Pharmacy and Bioallied Sciences antimicrobial efficacy q mix root canal irrigants silver nanoparticles sodium hypochlorite twin kleen |
| title | Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study |
| title_full | Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study |
| title_fullStr | Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study |
| title_full_unstemmed | Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study |
| title_short | Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study |
| title_sort | evaluation of antimicrobial efficacy of different irrigants mixed with silver nanoparticles an in vivo study |
| topic | antimicrobial efficacy q mix root canal irrigants silver nanoparticles sodium hypochlorite twin kleen |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_186_25 |
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