Evaluation of Antimicrobial Efficacy of Different Irrigants Mixed with Silver Nanoparticles – An In Vivo Study
Aim: To evaluate the antimicrobial efficacy of different irrigants combined with silver nanoparticles. Materials and Methods: Thirty-five patients were divided into seven groups (two control and five experimental), including Group 1: negative control (normal saline), Group 2: positive control (sodiu...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_186_25 |
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| Summary: | Aim:
To evaluate the antimicrobial efficacy of different irrigants combined with silver nanoparticles.
Materials and Methods:
Thirty-five patients were divided into seven groups (two control and five experimental), including Group 1: negative control (normal saline), Group 2: positive control (sodium hypochlorite), and Group 3 (sodium hypochlorite + AgNP), Group 4 (Twin Kleen), Group 5 (Twin Kleen + AgNP), Group 6 (Q Mix), and Group 7 (Q Mix + AgNP). Pre- and post-treatment bacterial samples were collected for analysis.
Results:
Sodium hypochlorite combined with silver nanoparticles demonstrated the highest antimicrobial efficacy among the tested irrigants, with a significant difference confirmed by the Chi-square statistical analysis.
Conclusion:
Within the limitations of the study, it can be concluded that sodium hypochlorite when mixed with the silver nanoparticles showed higher antimicrobial efficacy as compared to the other tested groups. |
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| ISSN: | 0976-4879 0975-7406 |