Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression
Purpose: To evaluate the efficacy of Highly Aspherical Lenslets (HAL) in slowing myopia progression among schoolchildren and compare it to orthokeratology. Methods: This retrospective study included 475 myopic patients aged 6 to 15 years, with myopia ranging from -0.75 to -5.75D Only the right eye o...
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Elsevier
2025-10-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100025002650 |
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| author | Chao Li Fan Yang WeiFen Gong |
| author_facet | Chao Li Fan Yang WeiFen Gong |
| author_sort | Chao Li |
| collection | DOAJ |
| description | Purpose: To evaluate the efficacy of Highly Aspherical Lenslets (HAL) in slowing myopia progression among schoolchildren and compare it to orthokeratology. Methods: This retrospective study included 475 myopic patients aged 6 to 15 years, with myopia ranging from -0.75 to -5.75D Only the right eye of each subject was analyzed. Cycloplegic refraction and axial length(AL) measurements were performed at baseline and after 6 months (only AL measurements were performed in the orthokeratology group after 6 months). Results: After 6 months, HAL lenses(0.00 [-0.25,0.00]D) significantly delayed spherical equivalent refraction (SER) myopia progression compared to single vision (SV) lenses(-0.50 [-0.75,-0.25]D) in both low and moderate myopia(P < 0.001). Additionally, both HAL (0.06 ± 0.10 mm) and orthokeratology(0.04 ± 0.13 mm) lenses significantly reduced AL elongation compared to SV lenses(0.25 ± 0.16 mm, (P < 0.001). However, there was no statistical difference between HAL and orthokeratology lenses in AL elongation(P = 0.157). In the low myopia group, HAL(0.05 ± 0.12 mm) and orthokeratology(0.09 ± 0.15 mm) lenses both significantly slowed AL elongation compared to SV lenses (0.27 ± 0.17 mm, P < 0.001), with HAL lenses showing a slight advantage over orthokeratology lenses(P = 0.038). In the moderate myopia group, both HAL(0.07 ± 0.09 mm) and orthokeratology(0 ± 0.10 mm) lenses significantly delayed AL elongation compared to SV lenses(0.22 ± 0.14 mm), with orthokeratology lenses having a stronger effect than HAL lenses(P < 0.001). Conclusions: HAL lenses demonstrate superior efficacy to SV lenses in mitigating myopia progression in both low and moderate myopia. Both HAL and orthokeratology lenses are effective in reducing AL elongation. Specifically, HAL lenses exhibit greater effectiveness in decreasing AL elongation in cases of low myopia, whereas Ortho-K lenses show a pronounced advantage in managing AL elongation in moderate myopia. |
| format | Article |
| id | doaj-art-36e74da183a8494ebf4e710b3f977059 |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-36e74da183a8494ebf4e710b3f9770592025-08-20T05:04:56ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-10-015510473310.1016/j.pdpdt.2025.104733Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progressionChao Li0Fan Yang1WeiFen Gong2Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, Guangdong Province, PR ChinaJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, Guangdong Province, PR ChinaCorresponding author at: Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Dongxia Road North, Jinping District, Shantou, Guangdong Province 515041, China.; Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, Guangdong Province, PR ChinaPurpose: To evaluate the efficacy of Highly Aspherical Lenslets (HAL) in slowing myopia progression among schoolchildren and compare it to orthokeratology. Methods: This retrospective study included 475 myopic patients aged 6 to 15 years, with myopia ranging from -0.75 to -5.75D Only the right eye of each subject was analyzed. Cycloplegic refraction and axial length(AL) measurements were performed at baseline and after 6 months (only AL measurements were performed in the orthokeratology group after 6 months). Results: After 6 months, HAL lenses(0.00 [-0.25,0.00]D) significantly delayed spherical equivalent refraction (SER) myopia progression compared to single vision (SV) lenses(-0.50 [-0.75,-0.25]D) in both low and moderate myopia(P < 0.001). Additionally, both HAL (0.06 ± 0.10 mm) and orthokeratology(0.04 ± 0.13 mm) lenses significantly reduced AL elongation compared to SV lenses(0.25 ± 0.16 mm, (P < 0.001). However, there was no statistical difference between HAL and orthokeratology lenses in AL elongation(P = 0.157). In the low myopia group, HAL(0.05 ± 0.12 mm) and orthokeratology(0.09 ± 0.15 mm) lenses both significantly slowed AL elongation compared to SV lenses (0.27 ± 0.17 mm, P < 0.001), with HAL lenses showing a slight advantage over orthokeratology lenses(P = 0.038). In the moderate myopia group, both HAL(0.07 ± 0.09 mm) and orthokeratology(0 ± 0.10 mm) lenses significantly delayed AL elongation compared to SV lenses(0.22 ± 0.14 mm), with orthokeratology lenses having a stronger effect than HAL lenses(P < 0.001). Conclusions: HAL lenses demonstrate superior efficacy to SV lenses in mitigating myopia progression in both low and moderate myopia. Both HAL and orthokeratology lenses are effective in reducing AL elongation. Specifically, HAL lenses exhibit greater effectiveness in decreasing AL elongation in cases of low myopia, whereas Ortho-K lenses show a pronounced advantage in managing AL elongation in moderate myopia.http://www.sciencedirect.com/science/article/pii/S1572100025002650Myopia controlMyopia defocusOrthokeratologyHighly aspherical lensletsMyopia |
| spellingShingle | Chao Li Fan Yang WeiFen Gong Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression Photodiagnosis and Photodynamic Therapy Myopia control Myopia defocus Orthokeratology Highly aspherical lenslets Myopia |
| title | Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression |
| title_full | Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression |
| title_fullStr | Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression |
| title_full_unstemmed | Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression |
| title_short | Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression |
| title_sort | comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression |
| topic | Myopia control Myopia defocus Orthokeratology Highly aspherical lenslets Myopia |
| url | http://www.sciencedirect.com/science/article/pii/S1572100025002650 |
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