The role of cytokines and interferons during pregnancy
Immune cells, cytokines, and interferons are key mediators that ensure the gestational process from implantation to childbirth. The coordination of their signaling pathways determines molecular interactions between the mother and the fetus, the physiological course of pregnancy and its outcomes, par...
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| Format: | Article |
| Language: | Russian |
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Kemerovo State Medical University
2024-09-01
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| Series: | Фундаментальная и клиническая медицина |
| Subjects: | |
| Online Access: | https://fcm.kemsmu.ru/jour/article/view/905 |
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| _version_ | 1849249066232315904 |
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| author | T. Е. Belokrinitskaya Yu. A. Vitkovsky N. I. Frolova |
| author_facet | T. Е. Belokrinitskaya Yu. A. Vitkovsky N. I. Frolova |
| author_sort | T. Е. Belokrinitskaya |
| collection | DOAJ |
| description | Immune cells, cytokines, and interferons are key mediators that ensure the gestational process from implantation to childbirth. The coordination of their signaling pathways determines molecular interactions between the mother and the fetus, the physiological course of pregnancy and its outcomes, particularly in the context of maternal respiratory viral infections. Here we analyze current information on physiological and pathological roles of cytokines and interferons during gestation in both uncomplicated and complicated pregnancies. Disrupted cytokine signaling might significantly alter fetal and placental development, leading to pregnancy complications and birth defects. |
| format | Article |
| id | doaj-art-36da1160c0704466a4a34e6bb017e92b |
| institution | Kabale University |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2024-09-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-36da1160c0704466a4a34e6bb017e92b2025-08-20T03:57:40ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412024-09-01939810810.23946/2500-0764-2024-9-3-98-108444The role of cytokines and interferons during pregnancyT. Е. Belokrinitskaya0Yu. A. Vitkovsky1N. I. Frolova2Chita State Medical AcademyMedlux Medical CenterChita State Medical AcademyImmune cells, cytokines, and interferons are key mediators that ensure the gestational process from implantation to childbirth. The coordination of their signaling pathways determines molecular interactions between the mother and the fetus, the physiological course of pregnancy and its outcomes, particularly in the context of maternal respiratory viral infections. Here we analyze current information on physiological and pathological roles of cytokines and interferons during gestation in both uncomplicated and complicated pregnancies. Disrupted cytokine signaling might significantly alter fetal and placental development, leading to pregnancy complications and birth defects.https://fcm.kemsmu.ru/jour/article/view/905cytokinesinterferonspregnancy |
| spellingShingle | T. Е. Belokrinitskaya Yu. A. Vitkovsky N. I. Frolova The role of cytokines and interferons during pregnancy Фундаментальная и клиническая медицина cytokines interferons pregnancy |
| title | The role of cytokines and interferons during pregnancy |
| title_full | The role of cytokines and interferons during pregnancy |
| title_fullStr | The role of cytokines and interferons during pregnancy |
| title_full_unstemmed | The role of cytokines and interferons during pregnancy |
| title_short | The role of cytokines and interferons during pregnancy |
| title_sort | role of cytokines and interferons during pregnancy |
| topic | cytokines interferons pregnancy |
| url | https://fcm.kemsmu.ru/jour/article/view/905 |
| work_keys_str_mv | AT tebelokrinitskaya theroleofcytokinesandinterferonsduringpregnancy AT yuavitkovsky theroleofcytokinesandinterferonsduringpregnancy AT nifrolova theroleofcytokinesandinterferonsduringpregnancy AT tebelokrinitskaya roleofcytokinesandinterferonsduringpregnancy AT yuavitkovsky roleofcytokinesandinterferonsduringpregnancy AT nifrolova roleofcytokinesandinterferonsduringpregnancy |