Glymphatic dysfunction evidenced by DTI-ALPS is related to obstructive sleep apnea intensity in newly diagnosed Parkinson’s disease

Glymphatic dysfunction evidenced by DTI-ALPS is related to obstructive sleep apnea intensity in newly diagnosed Parkinson’s disease

Abstract Glymphatic dysfunction potentially contributes to Parkinson’s disease (PD) via impaired clearance of metabolic waste products. Obstructive sleep apnea (OSA) can disturb sleep, which is necessary for proper glymphatic function, and is frequent in PD. We investigated the glymphatic function i...

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Bibliographic Details
Main Authors: Jiri Nepozitek, Stanislav Marecek, Veronika Rottova, Simona Dostalova, Tomas Krajca, Jiri Keller, Karel Sonka, Petr Dusek
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01018-8
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