Carcinoembryonic antigen trajectory predicts pathological complete response in advanced gastric cancer after neoadjuvant chemotherapy

Carcinoembryonic antigen trajectory predicts pathological complete response in advanced gastric cancer after neoadjuvant chemotherapy

AimsThis study aims to develop a simple, clinically applicable classification system to predict pCR based on carcinoembryonic antigen (CEA) trajectory during NAC.MethodsThis study included 366 AGC patients who received NAC followed by radical gastrectomy. CEA levels were measured before, during, and...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yonghe Chen, Dan Liu, Kaikai Wei, Yi Lin, Zhong Wang, Qian Sun, Huashe Wang, Junsheng Peng, Lei Lian
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Oncology
Subjects:	gastric cancer carcinoembryonic antigen trajectory analysis (TA) pathological complete response neoadjuvant chemotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1525324/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Impact of Helicobacter pylori infection on neoadjuvant chemotherapy in locally advanced gastric cancer: a retrospective analysis
by: Bin Zhong, et al.
Published: (2025-01-01)

Investigation of the expression level of methylated septin 9 gene and serological carcinoembryonic antigen to diagnose colorectal cancer. A meta-analysis study
by: Sharifeh Jorboniyan, et al.
Published: (2024-12-01)

Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma
by: Chengcheng Zhang, et al.
Published: (2023-05-01)

Corrigendum: Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma
by: Chengcheng Zhang, et al.
Published: (2025-01-01)

Prognostic Impact of the Postoperative Carcinoembryonic Antigen Level after Curative Resection of Locally Advanced Rectal Cancer
by: Ryoichi Tsukamoto, et al.
Published: (2025-01-01)

Nomogram for Predicting Survival in Advanced Gastric Cancer after Neoadjuvant Chemotherapy and Radical Surgery
by: Yonghe Chen, et al.
Published: (2021-01-01)

Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study
by: Zhouwei Zhan, et al.
Published: (2025-02-01)

Inflammatory burden index as a prognostic marker in patients with advanced gastric cancer treated with neoadjuvant chemotherapy and immunotherapy
by: Jiao-Bao Huang, et al.
Published: (2025-01-01)

Research trends of neoadjuvant therapy for breast cancer: A bibliometric analysis
by: Laiping Xie, et al.
Published: (2025-12-01)

Diabetic Ketoacidosis in Klinefelter Syndrome Sans Malignancy with Unusually Elevated Levels of CEA: A Case Report
by: Wo X, et al.
Published: (2025-01-01)

Immune microenvironment features underlying the superior efficacy of neoadjuvant immunochemotherapy over chemotherapy in local advanced gastric cancer
by: Ning Zhang, et al.
Published: (2025-01-01)

Breast Cancer: Neoadjuvant Chemotherapy
by: Barbara F. Shea, et al.
Published: (2015-05-01)

Breast Cancer: Neoadjuvant Chemotherapy
by: Barbara F. Shea, et al.
Published: (2015-05-01)

Combined morphology and radiomics of intravoxel incoherent movement as a predictive model for the pathologic complete response before neoadjuvant chemotherapy in patients with breast cancer
by: Yunyan Zheng, et al.
Published: (2025-02-01)

Monitoring Over Time of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Through an Ensemble Vision Transformers‐Based Model
by: Maria Colomba Comes, et al.
Published: (2024-12-01)

Efficacy and safety of neoadjuvant bevacizumab plus chemotherapy in locally advanced gastric cancer patients: a retrospective, comparative study
by: Bin Yin, et al.
Published: (2025-01-01)

Case report: Patients with positive HER-2 amplification locally advanced gastroesophageal junction cancer achieved pathologic complete response with the addition of pembrolizumab to chemotherapy plus trastuzumab as neoadjuvant therapy
by: Huanhuan Li, et al.
Published: (2025-02-01)

Predictive factors for axillary pathological complete response to neoadjuvant therapy in elderly breast cancer patients
by: Yuying Wang, et al.
Published: (2025-01-01)

Efficacy and safety of neoadjuvant immunotherapy combined with chemotherapy for stage II–IVa esophageal cancer: a network meta-analysis
by: Mingxing Wang, et al.
Published: (2025-01-01)

Indocyanine Green Fluorescence Plus Blue Dye for Sentinel Lymph Node Biopsy in Patients Undergoing Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter, Prospective Cohort Study
by: Miao Liu, et al.
Published: (2025-01-01)

Significance of Baseline and Changes of Tumor Markers and Neutrophil-to-Lymphocyte Ratio in Predicting Overall Survival for Patients with Advanced Pancreatic Adenocarcinoma: A Retrospective Analysis
by: Makoto Kadokura, et al.
Published: (2023-04-01)

Radiomics of magnetic resonance imaging for assessment of pathological complete response to neoadjuvant therapy and long-term survival in breast cancer
by: N. V. Petrova, et al.
Published: (2023-09-01)

Does Apoptotic Index Predict the Response to Neoadjuvant Chemotherapy in Patients with Breast Carcinoma?
by: Gokce ASKAN, et al.
Published: (2023-03-01)

Role of B7‐H3 in predicting response to neoadjuvant chemotherapy in muscle‐invasive bladder cancer
by: Ekamjit S. Deol, et al.
Published: (2024-11-01)

Neoadjuvant programmed death ligand-1 with chemotherapy versus chemotherapy alone for limited-stage small-cell lung cancer: a retrospective study
by: Zhi Yang, et al.
Published: (2025-01-01)

Clinical Effectiveness of Neoadjuvant Chemotherapy in Gastric Carcinoma and Exploration of Perioperative Imaging Assessment Parameters
by: Jiajun Lai, et al.
Published: (2021-01-01)

A case of de novo neuroendocrine prostate cancer presented with elevated level of serum CEA carrying BRCA2 mutation: case report and literature review
by: Weizhe Han, et al.
Published: (2025-01-01)

A deep learning approach for early prediction of breast cancer neoadjuvant chemotherapy response on multistage bimodal ultrasound images
by: Jiang Xie, et al.
Published: (2025-01-01)

Immunotherapy as a neoadjuvant preoperative treatment for locally advanced pulmonary sarcomatoid carcinoma: a case report of clinical efficacy
by: Hanhan Li, et al.
Published: (2025-01-01)

Impact of Neoadjuvant Chemotherapy and Preoperative Irradiation on Early Complications in Direct-to-Implant Breast Reconstruction
by: Ji Won Hwang, et al.
Published: (2024-09-01)

Dual-positive gastric cancer: an extremely malignant subtype of gastric cancer with high serum alpha-fetoprotein and carcinoembryonic antigen concentrations
by: Weixun Xie, et al.
Published: (2025-01-01)

First five years of Disciplinary and Interdisciplinary Science Education Research (DISER)
by: Xiufeng Liu, et al.
Published: (2025-02-01)

Multimodal treatment with Neoadjuvant chemotherapy for eyelid and periocular sebaceous gland carcinoma: Long-term outcomes
by: Vijitha S. Vempuluru, et al.
Published: (2025-06-01)

Design of studies on neoadjuvant therapy for intrahepatic cholangiocarcinoma
by: Yuan Cheng, et al.
Published: (2025-01-01)

Chemical cross‐linking facilitates antigen uptake and presentation and provides improved protection from Mpox with a dual‐antigen subunit vaccine
by: Long Chen, et al.
Published: (2025-01-01)

Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers
by: Lothar Häberle, et al.
Published: (2025-01-01)

Neoadjuvant chemoimmunotherapy for locally advanced squamous cell carcinoma of the head and neck: Systematic review and meta-analysis
by: Xiayi Zhu, et al.
Published: (2025-02-01)

Comparative survival outcomes of neoadjuvant and adjuvant therapy in patients with T1c, node-negative, triple-negative breast cancer: A population-based analysis
by: Yi-Zi Zheng, et al.
Published: (2025-02-01)

Comparative efficacy and safety of first-line neoadjuvant therapy for early-stage non-small cell lung cancer based on immune checkpoint inhibitor therapy: a systematic review and network meta-analysis
by: Linfeng Wang, et al.
Published: (2025-01-01)

Targeting BCMA in multiple myeloma: designs, challenges, and future directions
by: Yi Hu, et al.
Published: (2025-02-01)