Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear

Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear

ABSTRACT Background Muscular fatty infiltration originated from fibrogenic/adipogenic progenitors (FAPs) is a common issue following rotator cuff tear (RCT) that impairs shoulder function. RCT disrupted the biomechanical equilibrium of the shoulder and decreased the mechanical stimuli transmitted to...

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Bibliographic Details
Main Authors: Xingzuan Lin, Qingfa Song, Amila Kuati, Zhanghua Li, Hao Zhou, Shujing Feng, Minhui Wang, Siyuan Zhu, Guoqing Cui, Jianhua Wang, Xiexiang Shao
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
adipogenic differentiation
fibrogenic/adipogenic progenitors
low‐intensity pulsed ultrasound
Piezo‐type mechanosensitive ion channel component 1
rotator cuff tears
Online Access:https://doi.org/10.1002/jcsm.70004
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