Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle Damage

Background. Delayed-Onset Muscle Soreness (DOMS) is a phenomenon that arises from muscle damage following uncommon or intense eccentric exercise, with symptoms persisting  for a few days. The condition is characterized by muscle pain, reduced muscle strength, limited range of motion, and general dis...

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Main Authors: Roy Januardi Irawan, Joesoef Roepajadi, Heri Wahyudi, Nanda Rimawati, Mokhamad Nur Bawono, Ananda Perwira Bakti, Abdul Rohim Tualeka, Adi Wijayanto
Format: Article
Language:English
Published: OVS LLC 2025-07-01
Series:Physical Education Theory and Methodology
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Online Access:https://www.tmfv.com.ua/journal/article/view/3343
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author Roy Januardi Irawan
Joesoef Roepajadi
Heri Wahyudi
Nanda Rimawati
Mokhamad Nur Bawono
Ananda Perwira Bakti
Abdul Rohim Tualeka
Adi Wijayanto
author_facet Roy Januardi Irawan
Joesoef Roepajadi
Heri Wahyudi
Nanda Rimawati
Mokhamad Nur Bawono
Ananda Perwira Bakti
Abdul Rohim Tualeka
Adi Wijayanto
author_sort Roy Januardi Irawan
collection DOAJ
description Background. Delayed-Onset Muscle Soreness (DOMS) is a phenomenon that arises from muscle damage following uncommon or intense eccentric exercise, with symptoms persisting  for a few days. The condition is characterized by muscle pain, reduced muscle strength, limited range of motion, and general discomfort that affects performance and disrupts the exercise program. Objectives. This study aimed to investigate the effect of Selenium supplementation on DOMS and muscle damage after performing heavy eccentric exercise. Materials and methods. An experimental pre-post control group design was used in this study. A total of 44 male students from the Sports Science Department of the State University of Surabaya (Universitas Negeri Surabaya) were randomly and double-blindly assigned to either a selenium supplementation group (n = 22) or a placebo group (n = 22). The participants in both groups were instructed to consume one selenium or placebo capsule for 28 days. Following the 28-day supplementation period, both groups underwent a 10-set x 10-rep bench stepping-test. Delayed Onset Muscle Soreness (DOMS) and Creatine Kinase (CK) levels were assessed at 24 and 48 hours in the post-exercise phase. Results. The findings of the study demonstrated that during the 24 to 48-hour period following heavy eccentric exercise, both groups experienced a reduction in Delayed Onset Muscle Soreness (DOMS) and CK plasma levels. However, the selenium supplementation group exhibited a significantly greater reduction in DOMS and CK levels compared to the placebo group (p < 0.05). This suggests that selenium supplementation may enhance the natural recovery process, rather than being solely responsible for the observed reduction in these markers. Conclusions. In conclusion, Selenium supplementation may lower the likelihood of muscle injury following heavy eccentric exercise, as it effectively decreases plasma DOMS and CK levels in the bloodstream.
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spelling doaj-art-36c82327232c48d8a24d95f473797bd12025-08-20T03:34:47ZengOVS LLCPhysical Education Theory and Methodology1993-79891993-79972025-07-0125410.17309/tmfv.2025.4.03Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle DamageRoy Januardi Irawan0Joesoef Roepajadi1Heri Wahyudi2Nanda Rimawati3Mokhamad Nur Bawono4Ananda Perwira Bakti5Abdul Rohim Tualeka6Adi Wijayanto 7Universitas Negeri SurabayaUniversitas Negeri SurabayaUniversitas Negeri SurabayaUniversitas Negeri SurabayaUniversitas Negeri SurabayaUniversitas Negeri SurabayaUniversitas AirlanggaUniversitas Islam Sayyid Ali Rahmatullah Background. Delayed-Onset Muscle Soreness (DOMS) is a phenomenon that arises from muscle damage following uncommon or intense eccentric exercise, with symptoms persisting  for a few days. The condition is characterized by muscle pain, reduced muscle strength, limited range of motion, and general discomfort that affects performance and disrupts the exercise program. Objectives. This study aimed to investigate the effect of Selenium supplementation on DOMS and muscle damage after performing heavy eccentric exercise. Materials and methods. An experimental pre-post control group design was used in this study. A total of 44 male students from the Sports Science Department of the State University of Surabaya (Universitas Negeri Surabaya) were randomly and double-blindly assigned to either a selenium supplementation group (n = 22) or a placebo group (n = 22). The participants in both groups were instructed to consume one selenium or placebo capsule for 28 days. Following the 28-day supplementation period, both groups underwent a 10-set x 10-rep bench stepping-test. Delayed Onset Muscle Soreness (DOMS) and Creatine Kinase (CK) levels were assessed at 24 and 48 hours in the post-exercise phase. Results. The findings of the study demonstrated that during the 24 to 48-hour period following heavy eccentric exercise, both groups experienced a reduction in Delayed Onset Muscle Soreness (DOMS) and CK plasma levels. However, the selenium supplementation group exhibited a significantly greater reduction in DOMS and CK levels compared to the placebo group (p < 0.05). This suggests that selenium supplementation may enhance the natural recovery process, rather than being solely responsible for the observed reduction in these markers. Conclusions. In conclusion, Selenium supplementation may lower the likelihood of muscle injury following heavy eccentric exercise, as it effectively decreases plasma DOMS and CK levels in the bloodstream. https://www.tmfv.com.ua/journal/article/view/3343eccentric exercisemuscle damageInflammationsports injured
spellingShingle Roy Januardi Irawan
Joesoef Roepajadi
Heri Wahyudi
Nanda Rimawati
Mokhamad Nur Bawono
Ananda Perwira Bakti
Abdul Rohim Tualeka
Adi Wijayanto
Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle Damage
Physical Education Theory and Methodology
eccentric exercise
muscle damage
Inflammation
sports injured
title Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle Damage
title_full Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle Damage
title_fullStr Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle Damage
title_full_unstemmed Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle Damage
title_short Determining the Potential of L-Selenomethionine as a Protective Agent Against Exercise-Induced Muscle Damage
title_sort determining the potential of l selenomethionine as a protective agent against exercise induced muscle damage
topic eccentric exercise
muscle damage
Inflammation
sports injured
url https://www.tmfv.com.ua/journal/article/view/3343
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