Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s Disease

Polyuria after kidney transplantation causes graft dysfunction and increased thrombotic risk. We present a case of a polyuric adult with Dent’s disease who underwent staged bilateral native nephrectomies, the first operation before transplant and the second four months after transplant. This led to...

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Main Authors: Rosa M. Montero, Rachel Hilton, Jonathon Olsburgh
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2015/620371
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author Rosa M. Montero
Rachel Hilton
Jonathon Olsburgh
author_facet Rosa M. Montero
Rachel Hilton
Jonathon Olsburgh
author_sort Rosa M. Montero
collection DOAJ
description Polyuria after kidney transplantation causes graft dysfunction and increased thrombotic risk. We present a case of a polyuric adult with Dent’s disease who underwent staged bilateral native nephrectomies, the first operation before transplant and the second four months after transplant. This led to improved allograft function maintained during four years of follow-up. The retroperitoneal laparoscopic approach was well tolerated and allowed continuation of peritoneal dialysis before transplantation. A staged approach helps regulate fluid balance perioperatively and may be tailored to individual need according to posttransplant urine output. This novel approach should be considered for polyuric patients with tubular dysfunction including Dent’s disease.
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spelling doaj-art-36c3e37e23234b6fa609949bc2b4b5592025-08-20T02:07:41ZengWileyCase Reports in Transplantation2090-69432090-69512015-01-01201510.1155/2015/620371620371Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s DiseaseRosa M. Montero0Rachel Hilton1Jonathon Olsburgh2Department of Nephrology and Transplantation, Guy’s and St Thomas’ NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UKDepartment of Nephrology and Transplantation, Guy’s and St Thomas’ NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UKDepartment of Nephrology and Transplantation, Guy’s and St Thomas’ NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UKPolyuria after kidney transplantation causes graft dysfunction and increased thrombotic risk. We present a case of a polyuric adult with Dent’s disease who underwent staged bilateral native nephrectomies, the first operation before transplant and the second four months after transplant. This led to improved allograft function maintained during four years of follow-up. The retroperitoneal laparoscopic approach was well tolerated and allowed continuation of peritoneal dialysis before transplantation. A staged approach helps regulate fluid balance perioperatively and may be tailored to individual need according to posttransplant urine output. This novel approach should be considered for polyuric patients with tubular dysfunction including Dent’s disease.http://dx.doi.org/10.1155/2015/620371
spellingShingle Rosa M. Montero
Rachel Hilton
Jonathon Olsburgh
Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s Disease
Case Reports in Transplantation
title Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s Disease
title_full Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s Disease
title_fullStr Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s Disease
title_full_unstemmed Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s Disease
title_short Staged Hand-Assisted Bilateral Native Nephrectomy for Management of Posttransplant Polyuria in an Adult with Dent’s Disease
title_sort staged hand assisted bilateral native nephrectomy for management of posttransplant polyuria in an adult with dent s disease
url http://dx.doi.org/10.1155/2015/620371
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AT jonathonolsburgh stagedhandassistedbilateralnativenephrectomyformanagementofposttransplantpolyuriainanadultwithdentsdisease