PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE

SUMMERY The main objective of the management of patients with atrial fibrillation (AF) is an effective prevention of ischemic stroke. For this purpose indirect and direct oral anticoagulants may be used. The choice of anticoagulant should be based on a comprehensive assessment of a number of factors...

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Main Authors: A. V. Ardashev, I. V. Zotova
Format: Article
Language:Russian
Published: InterMedservice 2016-12-01
Series:Евразийский Кардиологический Журнал
Online Access:https://www.heartj.asia/jour/article/view/6194
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author A. V. Ardashev
I. V. Zotova
author_facet A. V. Ardashev
I. V. Zotova
author_sort A. V. Ardashev
collection DOAJ
description SUMMERY The main objective of the management of patients with atrial fibrillation (AF) is an effective prevention of ischemic stroke. For this purpose indirect and direct oral anticoagulants may be used. The choice of anticoagulant should be based on a comprehensive assessment of a number of factors - the presence of significant valvular disease, kidney function, potential drug interactions, risk of complications of anticoagulant therapy. Individual assessment of the profile of thromboembolic and hemorrhagic risks are largely determined by the age, can help choose an efficient anticoagulant with minimal risk of complications. In patients younger than 75 years, in the absence of contraindications to the use of direct oral anticoagulants, the drug of choice can be dabigatran, administered at a dose of 150 mg 2 b.i.d. Keywords: prevention of stroke, atrial fibrillation, cardiovascular disease, new oral anticoagulants.
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series Евразийский Кардиологический Журнал
spelling doaj-art-36c04311e24f4fa7aa6114afa292a7692025-08-20T03:58:59ZrusInterMedserviceЕвразийский Кардиологический Журнал2225-16852305-07482016-12-0104687510.38109/2225-1685-2016-4-68-756191PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGEA. V. Ardashev0I. V. Zotova1Federal research Clinical center for specialized types of health care and medical technologies of Federal Medical and Biology AgencyCentral State Medical Academy of the General Management Department of the President of RFSUMMERY The main objective of the management of patients with atrial fibrillation (AF) is an effective prevention of ischemic stroke. For this purpose indirect and direct oral anticoagulants may be used. The choice of anticoagulant should be based on a comprehensive assessment of a number of factors - the presence of significant valvular disease, kidney function, potential drug interactions, risk of complications of anticoagulant therapy. Individual assessment of the profile of thromboembolic and hemorrhagic risks are largely determined by the age, can help choose an efficient anticoagulant with minimal risk of complications. In patients younger than 75 years, in the absence of contraindications to the use of direct oral anticoagulants, the drug of choice can be dabigatran, administered at a dose of 150 mg 2 b.i.d. Keywords: prevention of stroke, atrial fibrillation, cardiovascular disease, new oral anticoagulants.https://www.heartj.asia/jour/article/view/6194
spellingShingle A. V. Ardashev
I. V. Zotova
PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE
Евразийский Кардиологический Журнал
title PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE
title_full PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE
title_fullStr PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE
title_full_unstemmed PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE
title_short PREVENTION OF STROKE IN ATRIAL FIBRILLATION: THE APPROACHES TO THE CHOICE OF ANTICOAGULANT, DEPENDING ON AGE
title_sort prevention of stroke in atrial fibrillation the approaches to the choice of anticoagulant depending on age
url https://www.heartj.asia/jour/article/view/6194
work_keys_str_mv AT avardashev preventionofstrokeinatrialfibrillationtheapproachestothechoiceofanticoagulantdependingonage
AT ivzotova preventionofstrokeinatrialfibrillationtheapproachestothechoiceofanticoagulantdependingonage