GSH-responsive targeted copper-based nanoparticle improve ovarian cancer treatment via induction of apoptosis-ferroptosis-cuproptosis
The combination of apoptosis-ferroptosis-cuproptosis provides a beneficial method for enhancing the curative effect of ovarian cancer (OC). In this study, we design and synthesize a nano-drug delivery platform, HTC@DOX, which is achieved by the self-assembly of an amphipathic molecule HA-SS-TOS-DTPA...
Saved in:
| Main Authors: | Li Ma, Sihong Guo, Xinlei Yang, Hongyu Gao, Jie Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
|
| Series: | Materials & Design |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127525003648 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Copper Metabolism and Cuproptosis in Ovarian Cancer
by: Yuhong Xu, et al.
Published: (2025-05-01) -
Characterization of tumor prognosis and sensitive chemotherapy drugs based on cuproptosis-related gene signature in ovarian cancer
by: Wei Tan, et al.
Published: (2025-01-01) -
Metformin Induces Apoptosis and Ferroptosis of Ovarian Cancer Cells Under Energy Stress Conditions
by: Yulun Wu, et al.
Published: (2025-02-01) -
Impact of diabetes and metformin on cuproptosis and ferroptosis in breast cancer patients: an immunohistochemical analysis
by: Changwen Li, et al.
Published: (2025-04-01) -
A GSH-consuming polymeric nanoparticles drives ferroptosis amplification and combines chemotherapy to amplify breast cancer treatment
by: Mingliang Pei, et al.
Published: (2025-07-01)