Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy

Porcine intestinal submucosa extracellular matrix (SIS-ECM) patches have shown promise as superior alternatives to synthetic materials for carotid endarterectomy. However, in the pressurized arterial environment, the mechanical strength of SIS-ECM patches may diminish during the remodeling process....

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Main Authors: Georgios S. Sfyroeras, MD, Constantinos N. Antonopoulos, MD, Andreas Panagiotopoulos, MD, Konstantinos G. Moulakakis, MD, Andreas M. Lazaris, MD, John D. Kakisis, MD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468428725001364
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author Georgios S. Sfyroeras, MD
Constantinos N. Antonopoulos, MD
Andreas Panagiotopoulos, MD
Konstantinos G. Moulakakis, MD
Andreas M. Lazaris, MD
John D. Kakisis, MD
author_facet Georgios S. Sfyroeras, MD
Constantinos N. Antonopoulos, MD
Andreas Panagiotopoulos, MD
Konstantinos G. Moulakakis, MD
Andreas M. Lazaris, MD
John D. Kakisis, MD
author_sort Georgios S. Sfyroeras, MD
collection DOAJ
description Porcine intestinal submucosa extracellular matrix (SIS-ECM) patches have shown promise as superior alternatives to synthetic materials for carotid endarterectomy. However, in the pressurized arterial environment, the mechanical strength of SIS-ECM patches may diminish during the remodeling process. This degradation can result in patch rupture and pseudoaneurysm formation. We report the case of a 77-year-old patient who experienced a rupture of the SIS-ECM patch 2 months post- carotid endarterectomy. The patient was successfully treated with saphenous vein patch reconstruction, resulting in a favorable outcome.
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issn 2468-4287
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publishDate 2025-08-01
publisher Elsevier
record_format Article
series Journal of Vascular Surgery Cases and Innovative Techniques
spelling doaj-art-369a2e3a557640f1b59f21d7a60c8e022025-08-20T02:48:49ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872025-08-0111410185410.1016/j.jvscit.2025.101854Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomyGeorgios S. Sfyroeras, MD0Constantinos N. Antonopoulos, MD1Andreas Panagiotopoulos, MD2Konstantinos G. Moulakakis, MD3Andreas M. Lazaris, MD4John D. Kakisis, MD5Correspondence: Georgios S. Sfyroeras, MD, First Department of Vascular Surgery, University of Athens Medical School, Attikon Hospital, 1, Rimini Str, Athens 12462, Greece; First Department of Vascular Surgery, University of Athens Medical School, Attikon Hospital, Athens, GreeceFirst Department of Vascular Surgery, University of Athens Medical School, Attikon Hospital, Athens, GreeceFirst Department of Vascular Surgery, University of Athens Medical School, Attikon Hospital, Athens, GreeceFirst Department of Vascular Surgery, University of Athens Medical School, Attikon Hospital, Athens, GreeceFirst Department of Vascular Surgery, University of Athens Medical School, Attikon Hospital, Athens, GreeceFirst Department of Vascular Surgery, University of Athens Medical School, Attikon Hospital, Athens, GreecePorcine intestinal submucosa extracellular matrix (SIS-ECM) patches have shown promise as superior alternatives to synthetic materials for carotid endarterectomy. However, in the pressurized arterial environment, the mechanical strength of SIS-ECM patches may diminish during the remodeling process. This degradation can result in patch rupture and pseudoaneurysm formation. We report the case of a 77-year-old patient who experienced a rupture of the SIS-ECM patch 2 months post- carotid endarterectomy. The patient was successfully treated with saphenous vein patch reconstruction, resulting in a favorable outcome.http://www.sciencedirect.com/science/article/pii/S2468428725001364Carotid endarterectomyPatchPorcine intestinal submucosa extracellular matrix patchPseudoaneurysmRupture
spellingShingle Georgios S. Sfyroeras, MD
Constantinos N. Antonopoulos, MD
Andreas Panagiotopoulos, MD
Konstantinos G. Moulakakis, MD
Andreas M. Lazaris, MD
John D. Kakisis, MD
Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy
Journal of Vascular Surgery Cases and Innovative Techniques
Carotid endarterectomy
Patch
Porcine intestinal submucosa extracellular matrix patch
Pseudoaneurysm
Rupture
title Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy
title_full Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy
title_fullStr Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy
title_full_unstemmed Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy
title_short Porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy
title_sort porcine intestinal submucosa extracellular matrix patch rupture after carotid endarterectomy
topic Carotid endarterectomy
Patch
Porcine intestinal submucosa extracellular matrix patch
Pseudoaneurysm
Rupture
url http://www.sciencedirect.com/science/article/pii/S2468428725001364
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