Development and mechanistic investigation of recombinant type III humanized collagen gel for mid-facial soft tissue repair

Abstract Mid-facial depression is a key sign of facial aging, primarily caused by the loss of collagen leading to depletion of the extracellular matrix (ECM). However, the existing fillers for soft tissue augmentation have shown certain limitations in repairing mid-facial depression. Therefore, we h...

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Main Authors: Qian Wang, Qifei An, Yuanzhou Wang, Jingbo Yang, Xiujuan Zhang, Shibo Jiang, Min Chen, Lu Lu, Yun Zhu
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:Collagen and Leather
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Online Access:https://doi.org/10.1186/s42825-025-00196-8
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