Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections
Introduction: Whooping cough-like respiratory tract infections (WCLRTI) caused by factors other than the Bordetella pertussis are available. Clinical picture is difficult to differentiate between the B. pertussis and viral respiratory infections. Methodology: Eighty-five patients with the diagno...
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The Journal of Infection in Developing Countries
2019-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/10558 |
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| author | Suna Selbuz Ergin Çiftçi Halil Özdemir Haluk Güriz Erdal İnce |
| author_facet | Suna Selbuz Ergin Çiftçi Halil Özdemir Haluk Güriz Erdal İnce |
| author_sort | Suna Selbuz |
| collection | DOAJ |
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Introduction: Whooping cough-like respiratory tract infections (WCLRTI) caused by factors other than the Bordetella pertussis are available. Clinical picture is difficult to differentiate between the B. pertussis and viral respiratory infections.
Methodology: Eighty-five patients with the diagnosis of WCLRTI were divided into 3 groups. Group 1 involved patients with pertussis shown by nasopharyngeal aspirate culture (NAC) and/or PCR. Group 2 consisted of patients who B. pertussis was not detected by NAC however, clinicians still evaluated them as potential patients of pertussis. Group 3 involved patients with the diagnosis of WCLRTI and those with VRTI detected by antigen detection/PCR.
Results: Patients with pertussis had longer duration of the symptoms prior to admission. Paroxysmal cough, whooping, vomiting after coughing, cyanosis, apnea, seizures and abdominal hernias were more common in patients with pertussis. Fever, wheezing, tachypnea, retraction, fine crackles and rhonchi were more common in Group 3. Chest radiographs of patients in Group 3 revealed more bronchopneumonic infiltration, increased aeration, and atelectasis. CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate) were significantly higher in Group 3. Of the patients 43.6% had no pertussis vaccination due to being < 2 months in age and 29.4% had 1 dose.
Conclusions: Pertussis should be thought in differential diagnosis of children with complaints of episodes of paroxysmal cough, cough accompanied by gasping, vomiting after coughing; with leukocytosis, lymphocytosis and a normal chest X-ray. The majority of children with pertussis infection are those who have not had the opportunity for vaccination.
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| format | Article |
| id | doaj-art-368ea6b2b1c74564904e0a4b3a4e2e37 |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2019-09-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-368ea6b2b1c74564904e0a4b3a4e2e372025-08-20T02:57:21ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802019-09-01130910.3855/jidc.10558Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infectionsSuna Selbuz0Ergin Çiftçi1Halil Özdemir2Haluk Güriz3Erdal İnce4Department of Pediatrics, Faculty of Medicine, Ankara University, Ankara, TurkeyDepartment of Pediatric Infectious Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey Department of Pediatric Infectious Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey Microbiology Laboratory, Faculty of Medicine, Ankara University, Ankara, TurkeyDepartment of Pediatric Infectious Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey Introduction: Whooping cough-like respiratory tract infections (WCLRTI) caused by factors other than the Bordetella pertussis are available. Clinical picture is difficult to differentiate between the B. pertussis and viral respiratory infections. Methodology: Eighty-five patients with the diagnosis of WCLRTI were divided into 3 groups. Group 1 involved patients with pertussis shown by nasopharyngeal aspirate culture (NAC) and/or PCR. Group 2 consisted of patients who B. pertussis was not detected by NAC however, clinicians still evaluated them as potential patients of pertussis. Group 3 involved patients with the diagnosis of WCLRTI and those with VRTI detected by antigen detection/PCR. Results: Patients with pertussis had longer duration of the symptoms prior to admission. Paroxysmal cough, whooping, vomiting after coughing, cyanosis, apnea, seizures and abdominal hernias were more common in patients with pertussis. Fever, wheezing, tachypnea, retraction, fine crackles and rhonchi were more common in Group 3. Chest radiographs of patients in Group 3 revealed more bronchopneumonic infiltration, increased aeration, and atelectasis. CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate) were significantly higher in Group 3. Of the patients 43.6% had no pertussis vaccination due to being < 2 months in age and 29.4% had 1 dose. Conclusions: Pertussis should be thought in differential diagnosis of children with complaints of episodes of paroxysmal cough, cough accompanied by gasping, vomiting after coughing; with leukocytosis, lymphocytosis and a normal chest X-ray. The majority of children with pertussis infection are those who have not had the opportunity for vaccination. https://jidc.org/index.php/journal/article/view/10558Bordetella pertussispediatric intensive care unitpertussis vaccinewhooping cough |
| spellingShingle | Suna Selbuz Ergin Çiftçi Halil Özdemir Haluk Güriz Erdal İnce Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections Journal of Infection in Developing Countries Bordetella pertussis pediatric intensive care unit pertussis vaccine whooping cough |
| title | Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections |
| title_full | Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections |
| title_fullStr | Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections |
| title_full_unstemmed | Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections |
| title_short | Comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections |
| title_sort | comparison of the clinical and laboratory characteristics of pertussis or viral lower respiratory tract infections |
| topic | Bordetella pertussis pediatric intensive care unit pertussis vaccine whooping cough |
| url | https://jidc.org/index.php/journal/article/view/10558 |
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