Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique
We present a case of a 66-year-old man with a three-year history of Gleason 10 prostate cancer (PCa), who presented with penile pain, erythema, and induration of the penile shaft. His cancer was treated with androgen deprivation therapy (ADT), radiotherapy, and apalutamide, resulting in PSA reductio...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Urology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442024002535 |
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| author | M. Vukovic M. Albijanic N. Radovic |
| author_facet | M. Vukovic M. Albijanic N. Radovic |
| author_sort | M. Vukovic |
| collection | DOAJ |
| description | We present a case of a 66-year-old man with a three-year history of Gleason 10 prostate cancer (PCa), who presented with penile pain, erythema, and induration of the penile shaft. His cancer was treated with androgen deprivation therapy (ADT), radiotherapy, and apalutamide, resulting in PSA reduction; however, a solitary penile lesion persisted, necessitating radical penectomy. At 12 months post-surgery, PSA levels and magnetic resonance imaging findings remained stable, with no signs of metastasis. This case highlights the viability of radical penectomy for solitary penile metastasis in hormone-sensitive metastatic prostate cancer (mHSPC), with potential benefits for symptom control and survival. |
| format | Article |
| id | doaj-art-3685e7b437544ca398bd9cedf48d931b |
| institution | Kabale University |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-3685e7b437544ca398bd9cedf48d931b2025-01-14T04:12:18ZengElsevierUrology Case Reports2214-44202025-01-0158102899Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical techniqueM. Vukovic0M. Albijanic1N. Radovic2Corresponding author.; Department of Urology, Clinical Centre of Montenegro, Ljubljanska bb, 81000, Podgorica, MontenegroDepartment of Urology, Clinical Centre of Montenegro, Ljubljanska bb, 81000, Podgorica, MontenegroDepartment of Urology, Clinical Centre of Montenegro, Ljubljanska bb, 81000, Podgorica, MontenegroWe present a case of a 66-year-old man with a three-year history of Gleason 10 prostate cancer (PCa), who presented with penile pain, erythema, and induration of the penile shaft. His cancer was treated with androgen deprivation therapy (ADT), radiotherapy, and apalutamide, resulting in PSA reduction; however, a solitary penile lesion persisted, necessitating radical penectomy. At 12 months post-surgery, PSA levels and magnetic resonance imaging findings remained stable, with no signs of metastasis. This case highlights the viability of radical penectomy for solitary penile metastasis in hormone-sensitive metastatic prostate cancer (mHSPC), with potential benefits for symptom control and survival.http://www.sciencedirect.com/science/article/pii/S2214442024002535Penile metastasisRadical penectomy |
| spellingShingle | M. Vukovic M. Albijanic N. Radovic Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique Urology Case Reports Penile metastasis Radical penectomy |
| title | Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique |
| title_full | Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique |
| title_fullStr | Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique |
| title_full_unstemmed | Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique |
| title_short | Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique |
| title_sort | total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer mhspc case report with surgical technique |
| topic | Penile metastasis Radical penectomy |
| url | http://www.sciencedirect.com/science/article/pii/S2214442024002535 |
| work_keys_str_mv | AT mvukovic totalpenectomyastreatmentoptionforsolitarypenilemetastasisinhormonesensitivemetastaticprostatecancermhspccasereportwithsurgicaltechnique AT malbijanic totalpenectomyastreatmentoptionforsolitarypenilemetastasisinhormonesensitivemetastaticprostatecancermhspccasereportwithsurgicaltechnique AT nradovic totalpenectomyastreatmentoptionforsolitarypenilemetastasisinhormonesensitivemetastaticprostatecancermhspccasereportwithsurgicaltechnique |