Management of myelofibrosis during pregnancy: A case report

Introduction. Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm that occurs most commonly in the decade six of life and it is very rare in the young persons. Case report. We reported a 28-year-old female patient with primary myelofibrosis who had a normal pregnancy and del...

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Main Authors: Živković Radmila, Marković Olivera, Marisavljević Dragomir, Terzić Tatjana, Tukić Ljiljana
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2015-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501504383Z.pdf
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author Živković Radmila
Marković Olivera
Marisavljević Dragomir
Terzić Tatjana
Tukić Ljiljana
author_facet Živković Radmila
Marković Olivera
Marisavljević Dragomir
Terzić Tatjana
Tukić Ljiljana
author_sort Živković Radmila
collection DOAJ
description Introduction. Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm that occurs most commonly in the decade six of life and it is very rare in the young persons. Case report. We reported a 28-year-old female patient with primary myelofibrosis who had a normal pregnancy and delivery in the week 40 of pregnancy without any complications. Two years before the diagnosis of PMF she had normal pregnancy. The patient was treated with interferon-alpha and low dose aspirin during the whole pregnancy and with low-molecular-weight heparin a week before delivery and 6 weeks after. The patient had no complications during pregnancy. She delivered in term with healthy, normal baby weight. Conclusion. Decision about treatment strategy of pregnancy associated hematologic malignancies should be made for each patient individually.
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issn 0042-8450
language English
publishDate 2015-01-01
publisher Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
record_format Article
series Vojnosanitetski Pregled
spelling doaj-art-367e2ea0730f43dcba99bb7585d61a7c2025-08-20T03:18:45ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502015-01-0172438338510.2298/VSP1504383Z0042-84501504383ZManagement of myelofibrosis during pregnancy: A case reportŽivković Radmila0Marković Olivera1Marisavljević Dragomir2Terzić Tatjana3Tukić Ljiljana4Clinical Hospital Center ”Bežanijska kosa“, Department of Hematology, BelgradeClinical Hospital Center ”Bežanijska kosa“, Department of Hematology, Belgrade + Faculty of Medicine, BelgradeClinical Hospital Center ”Bežanijska kosa“, Department of Hematology, Belgrade + Faculty of Medicine, BelgradeFaculty of Medicine, Institute of Pathology, BelgradeMilitary Medical Academy, Clinic of Hematology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeIntroduction. Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm that occurs most commonly in the decade six of life and it is very rare in the young persons. Case report. We reported a 28-year-old female patient with primary myelofibrosis who had a normal pregnancy and delivery in the week 40 of pregnancy without any complications. Two years before the diagnosis of PMF she had normal pregnancy. The patient was treated with interferon-alpha and low dose aspirin during the whole pregnancy and with low-molecular-weight heparin a week before delivery and 6 weeks after. The patient had no complications during pregnancy. She delivered in term with healthy, normal baby weight. Conclusion. Decision about treatment strategy of pregnancy associated hematologic malignancies should be made for each patient individually.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501504383Z.pdfmyeloproliferative disordersprimary myelofibrosispregnancyinterferon-alphatreatment outcome
spellingShingle Živković Radmila
Marković Olivera
Marisavljević Dragomir
Terzić Tatjana
Tukić Ljiljana
Management of myelofibrosis during pregnancy: A case report
Vojnosanitetski Pregled
myeloproliferative disorders
primary myelofibrosis
pregnancy
interferon-alpha
treatment outcome
title Management of myelofibrosis during pregnancy: A case report
title_full Management of myelofibrosis during pregnancy: A case report
title_fullStr Management of myelofibrosis during pregnancy: A case report
title_full_unstemmed Management of myelofibrosis during pregnancy: A case report
title_short Management of myelofibrosis during pregnancy: A case report
title_sort management of myelofibrosis during pregnancy a case report
topic myeloproliferative disorders
primary myelofibrosis
pregnancy
interferon-alpha
treatment outcome
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501504383Z.pdf
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AT markovicolivera managementofmyelofibrosisduringpregnancyacasereport
AT marisavljevicdragomir managementofmyelofibrosisduringpregnancyacasereport
AT terzictatjana managementofmyelofibrosisduringpregnancyacasereport
AT tukicljiljana managementofmyelofibrosisduringpregnancyacasereport