CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION
SUMMERY The patient with diagnosis of idiopathic pulmonary hypertension, functional class III (WHO) was treated by anticoagulants, diuretics. After 6 months of treatment with phosphodiesterase type 5-inhibitor sildenafil, there was observed the negative dynamic with systolic pulmonary arterial press...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
InterMedservice
2016-12-01
|
| Series: | Евразийский Кардиологический Журнал |
| Online Access: | https://www.heartj.asia/jour/article/view/6196 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850049194646044672 |
|---|---|
| author | I. N. Taran V. M. Paramonov Z. S. Valieva M. A. Saidova S. N. Nakonechnikov T. V. Martynyuk I. Ye. Chazova |
| author_facet | I. N. Taran V. M. Paramonov Z. S. Valieva M. A. Saidova S. N. Nakonechnikov T. V. Martynyuk I. Ye. Chazova |
| author_sort | I. N. Taran |
| collection | DOAJ |
| description | SUMMERY The patient with diagnosis of idiopathic pulmonary hypertension, functional class III (WHO) was treated by anticoagulants, diuretics. After 6 months of treatment with phosphodiesterase type 5-inhibitor sildenafil, there was observed the negative dynamic with systolic pulmonary arterial pressure, intolerance to exercises. The treatment goals were not achieved with sildenafil therapy. The transitioning from sildenafil to riociguat therapy was done. By 6 months of the riociguat therapy there was achieved the significant improvement of the functional and hemodynamic status. Ам^^ to the stratification risk scale the treatment goals were reached. Keywords: idiopathic pulmonary hypertension, phosphodiester-ase type 5 inhibitor, sildenafil, soluble guanylate cyclase stimulators, riociguat, risk assessment. |
| format | Article |
| id | doaj-art-3676441ad0e146bf976e7335f052df20 |
| institution | DOAJ |
| issn | 2225-1685 2305-0748 |
| language | Russian |
| publishDate | 2016-12-01 |
| publisher | InterMedservice |
| record_format | Article |
| series | Евразийский Кардиологический Журнал |
| spelling | doaj-art-3676441ad0e146bf976e7335f052df202025-08-20T02:53:46ZrusInterMedserviceЕвразийский Кардиологический Журнал2225-16852305-07482016-12-0104849310.38109/2225-1685-2016-4-84-936193CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSIONI. N. Taran0V. M. Paramonov1Z. S. Valieva2M. A. Saidova3S. N. Nakonechnikov4T. V. Martynyuk5I. Ye. Chazova6Russian Cardiology Research and Production ComplexRussian Cardiology Research and Production ComplexRussian Cardiology Research and Production ComplexRussian Cardiology Research and Production ComplexRussian Cardiology Research and Production ComplexRussian Cardiology Research and Production ComplexRussian Cardiology Research and Production ComplexSUMMERY The patient with diagnosis of idiopathic pulmonary hypertension, functional class III (WHO) was treated by anticoagulants, diuretics. After 6 months of treatment with phosphodiesterase type 5-inhibitor sildenafil, there was observed the negative dynamic with systolic pulmonary arterial pressure, intolerance to exercises. The treatment goals were not achieved with sildenafil therapy. The transitioning from sildenafil to riociguat therapy was done. By 6 months of the riociguat therapy there was achieved the significant improvement of the functional and hemodynamic status. Ам^^ to the stratification risk scale the treatment goals were reached. Keywords: idiopathic pulmonary hypertension, phosphodiester-ase type 5 inhibitor, sildenafil, soluble guanylate cyclase stimulators, riociguat, risk assessment.https://www.heartj.asia/jour/article/view/6196 |
| spellingShingle | I. N. Taran V. M. Paramonov Z. S. Valieva M. A. Saidova S. N. Nakonechnikov T. V. Martynyuk I. Ye. Chazova CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION Евразийский Кардиологический Журнал |
| title | CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION |
| title_full | CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION |
| title_fullStr | CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION |
| title_full_unstemmed | CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION |
| title_short | CLINICAL CASE: OPPORTUNITY OF THERAPY OPTIMIZATION DUE TO TRANSITIONING FROM SILDENAFIL TO RIOCIGUAT IN PATIENT WITH IDIOPATHIC PULMONARY HYPERTENSION |
| title_sort | clinical case opportunity of therapy optimization due to transitioning from sildenafil to riociguat in patient with idiopathic pulmonary hypertension |
| url | https://www.heartj.asia/jour/article/view/6196 |
| work_keys_str_mv | AT intaran clinicalcaseopportunityoftherapyoptimizationduetotransitioningfromsildenafiltoriociguatinpatientwithidiopathicpulmonaryhypertension AT vmparamonov clinicalcaseopportunityoftherapyoptimizationduetotransitioningfromsildenafiltoriociguatinpatientwithidiopathicpulmonaryhypertension AT zsvalieva clinicalcaseopportunityoftherapyoptimizationduetotransitioningfromsildenafiltoriociguatinpatientwithidiopathicpulmonaryhypertension AT masaidova clinicalcaseopportunityoftherapyoptimizationduetotransitioningfromsildenafiltoriociguatinpatientwithidiopathicpulmonaryhypertension AT snnakonechnikov clinicalcaseopportunityoftherapyoptimizationduetotransitioningfromsildenafiltoriociguatinpatientwithidiopathicpulmonaryhypertension AT tvmartynyuk clinicalcaseopportunityoftherapyoptimizationduetotransitioningfromsildenafiltoriociguatinpatientwithidiopathicpulmonaryhypertension AT iyechazova clinicalcaseopportunityoftherapyoptimizationduetotransitioningfromsildenafiltoriociguatinpatientwithidiopathicpulmonaryhypertension |