Real-world evidence of chemotherapy effects in advanced pancreatic ductal adenocarcinoma: prognostic significance of TP53 status in gemcitabine plus nab-paclitaxel therapy
Background: Gemcitabine plus nab-paclitaxel (GnP) and FOLFIRINOX (FFX) therapies are widely used to treat advanced pancreatic ductal adenocarcinoma (PDAC). This study aimed to identify the prognostic factors associated with these regimens, focusing on key genomic alterations in the ‘Big Four’ genes...
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| Main Authors: | M. Sugimori, A. Hirotani, H. Yamazaki, M. Oshi, K. Kawashima, H. Tsuchiya, Y. Kanemaru, Y. Suzuki, S. Onodera, H. Miwa, A. Nozaki, K. Sugimori, C. Kunisaki, M. Kudo, M. Morimoto, S. Maeda |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | ESMO Gastrointestinal Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949819825000901 |
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