Delta Radiomics — Potential role in Head Neck Cancer

Introduction: Delta radiomics is a tool used to assess the response of oncologic patients undergoing immunotherapy. It extracts high-dimensional quantitative features from medical images, providing information about cancer's phenotype, genotype, and tumoral microenvironment. This analysis could...

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Main Author: Shrikant B. Mali
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Oral Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906024005223
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author Shrikant B. Mali
author_facet Shrikant B. Mali
author_sort Shrikant B. Mali
collection DOAJ
description Introduction: Delta radiomics is a tool used to assess the response of oncologic patients undergoing immunotherapy. It extracts high-dimensional quantitative features from medical images, providing information about cancer's phenotype, genotype, and tumoral microenvironment. This analysis could help avoid invasive procedures and help choose the most suitable therapeutic in multiple therapeutic options. Radiomics has gained interest as an imaging biomarker for predicting response to various immunotherapies. Delta radiomics assesses feature variations from one time point to another based on subsequent images, offering higher value for treatment-outcome prediction or patient stratification into risk categories. It has potential benefits for clinical endpoints in oncology, such as differential diagnosis, prognosis, treatment response prediction, and evaluation of side effects. Further research with prospective and multicentre studies is needed for clinical validation of delta radiomics approaches. Statement of clinical significance: In head and neck oncology, delta radiomics can be used to enhance the precision of diagnosis, assess tumor response, forecast normal tissue toxicity, predict clinical outcome, and pinpoint characteristics for treatment modification. Patients' quality of life may be enhanced by it. It can support post-treatment surveillance. Additionally, it can support the delivery of individualized care based on a patient's reaction to medication and radiation.
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spelling doaj-art-366e068e894a483fb1e4a5446437ec3a2025-08-20T02:31:27ZengElsevierOral Oncology Reports2772-90602024-12-011210067610.1016/j.oor.2024.100676Delta Radiomics — Potential role in Head Neck CancerShrikant B. Mali0Mahatma Gandhi Vidya Mandir's Dental College and Hospital, Nashik, IndiaIntroduction: Delta radiomics is a tool used to assess the response of oncologic patients undergoing immunotherapy. It extracts high-dimensional quantitative features from medical images, providing information about cancer's phenotype, genotype, and tumoral microenvironment. This analysis could help avoid invasive procedures and help choose the most suitable therapeutic in multiple therapeutic options. Radiomics has gained interest as an imaging biomarker for predicting response to various immunotherapies. Delta radiomics assesses feature variations from one time point to another based on subsequent images, offering higher value for treatment-outcome prediction or patient stratification into risk categories. It has potential benefits for clinical endpoints in oncology, such as differential diagnosis, prognosis, treatment response prediction, and evaluation of side effects. Further research with prospective and multicentre studies is needed for clinical validation of delta radiomics approaches. Statement of clinical significance: In head and neck oncology, delta radiomics can be used to enhance the precision of diagnosis, assess tumor response, forecast normal tissue toxicity, predict clinical outcome, and pinpoint characteristics for treatment modification. Patients' quality of life may be enhanced by it. It can support post-treatment surveillance. Additionally, it can support the delivery of individualized care based on a patient's reaction to medication and radiation.http://www.sciencedirect.com/science/article/pii/S2772906024005223
spellingShingle Shrikant B. Mali
Delta Radiomics — Potential role in Head Neck Cancer
Oral Oncology Reports
title Delta Radiomics — Potential role in Head Neck Cancer
title_full Delta Radiomics — Potential role in Head Neck Cancer
title_fullStr Delta Radiomics — Potential role in Head Neck Cancer
title_full_unstemmed Delta Radiomics — Potential role in Head Neck Cancer
title_short Delta Radiomics — Potential role in Head Neck Cancer
title_sort delta radiomics potential role in head neck cancer
url http://www.sciencedirect.com/science/article/pii/S2772906024005223
work_keys_str_mv AT shrikantbmali deltaradiomicspotentialroleinheadneckcancer