In vitro investigations of chemical composition, antibacterial, antioxidant, antidiabetic, and anti-inflammatory activities of Chromolaena odorata flower extracts
The purpose of this study was to conduct preliminary investigations into the chemical composition and biological characteristics of Chromolaena odorata flower extracts. The results revealed that C. odorata flowers include alkaloids, flavonoids, glycosides, phenols, tannins, triterpenoids, and sapo...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Prince of Songkla University
2024-12-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
| Subjects: | |
| Online Access: | https://sjst.psu.ac.th/journal/46-6/6.pdf |
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| Summary: | The purpose of this study was to conduct preliminary investigations into the chemical composition and biological
characteristics of Chromolaena odorata flower extracts. The results revealed that C. odorata flowers include alkaloids,
flavonoids, glycosides, phenols, tannins, triterpenoids, and saponins. The antibacterial activity of the extracts was assessed using
the antibacterial ring diameter, minimum inhibitory concentration, and minimum bactericidal concentration. The extracts were
more efficient against Gram-positive bacteria than Gram-negative bacteria, with minimum bactericidal concentrations ranging
from 125 to 1000 µg/mL. C. odorata flower extracts had significant antioxidant and anti-inflammatory activity, with IC50 values
ranging from 10.44±0.46 to 152.81±8.63 µg/mL. Ethyl acetate fraction extracted from C. odorata flowers showed the ability to
more effectively inhibit α-amylase (IC50 = 109.24±1.12 µg/mL) and α-glucosidase (IC50 = 53.87±0.42 µg/mL) than the other
remaining fractions. These findings indicate that C. odorata flowers might be used as a natural source of antibacterial,
antioxidant, antidiabetic, and anti-inflammatory compounds. |
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| ISSN: | 0125-3395 |