Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes)
ObjectivesThis study aimed to evaluate the impact of Continuous Glucose Monitoring (CGM) on enhanced recovery after surgery (ERAS) outcomes in colorectal cancer (CRC) patients with type 2 diabetes mellitus (T2DM).MethodsWe conducted an observational cohort study of adult patients (≥18 years) with T2...
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1464071/full |
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| author | Qinbo Wang Qinbo Wang Qinbo Wang Yuan Zhou Yuan Zhou Wanzhen Wang Wanzhen Wang Yingjuan Ou Yingjuan Ou Yingjuan Ou Xia Wu Xia Wu Junrong Chen Junrong Chen Junrong Chen Xiaoyan Li Xiaoyan Li Hua Li Hua Li |
| author_facet | Qinbo Wang Qinbo Wang Qinbo Wang Yuan Zhou Yuan Zhou Wanzhen Wang Wanzhen Wang Yingjuan Ou Yingjuan Ou Yingjuan Ou Xia Wu Xia Wu Junrong Chen Junrong Chen Junrong Chen Xiaoyan Li Xiaoyan Li Hua Li Hua Li |
| author_sort | Qinbo Wang |
| collection | DOAJ |
| description | ObjectivesThis study aimed to evaluate the impact of Continuous Glucose Monitoring (CGM) on enhanced recovery after surgery (ERAS) outcomes in colorectal cancer (CRC) patients with type 2 diabetes mellitus (T2DM).MethodsWe conducted an observational cohort study of adult patients (≥18 years) with T2DM undergoing abdominal surgery for pathologically confirmed CRC. Exclusion criteria included history of other malignancies, preoperative infections, or incomplete clinical data. Participants were stratified into two groups: the exposed group (CGM monitoring) and the control group (conventional glucose analyzer [CGA]). Primary outcomes included glycemic variability, surgical complications, ERAS milestones, and patient satisfaction scores.ResultsAmong 181 enrolled patients (CGM = 81, CGA = 100), CGM demonstrated superior glycemic control compared to CGA, with significantly lower mean daily glucose levels at postoperative day 1 (9.52 ± 2.53 vs. 10.37 ± 2.26 mmol/L, p < 0.05) and day 3 (9.36 ± 1.82 vs. 10.64 ± 1.84 mmol/L, p < 0.05). The CGM group showed better clinical outcomes including improved anastomotic healing (p < 0.05), shorter time to first flatus (p < 0.05), and reduced length of hospitalization (p < 0.05). Patient satisfaction scores were significantly higher in the CGM group (32.42 ± 3.33 vs. 29.81 ± 2.98, p < 0.05).ConclusionCGM provides superior perioperative glucose monitoring in diabetic CRC patients, particularly during the critical 72-h postoperative period. The technology facilitates early detection of acute hyperglycemia, promotes wound healing, and accelerates recovery within ERAS protocols. These findings support the clinical value of CGM implementation in surgical management of T2DM patients with CRC. |
| format | Article |
| id | doaj-art-366926ba2cd0468db3147ed25da38c4c |
| institution | OA Journals |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-366926ba2cd0468db3147ed25da38c4c2025-08-20T02:09:06ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-06-011210.3389/fmed.2025.14640711464071Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes)Qinbo Wang0Qinbo Wang1Qinbo Wang2Yuan Zhou3Yuan Zhou4Wanzhen Wang5Wanzhen Wang6Yingjuan Ou7Yingjuan Ou8Yingjuan Ou9Xia Wu10Xia Wu11Junrong Chen12Junrong Chen13Junrong Chen14Xiaoyan Li15Xiaoyan Li16Hua Li17Hua Li18Department of Pharmacy, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaDepartment of Graceland Medical Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaDepartment of Graceland Medical Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Pharmacy, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaDepartment of Graceland Medical Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Graceland Medical Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Graceland Medical Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of General Practice, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Pharmacy, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Graceland Medical Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ChinaBiomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaObjectivesThis study aimed to evaluate the impact of Continuous Glucose Monitoring (CGM) on enhanced recovery after surgery (ERAS) outcomes in colorectal cancer (CRC) patients with type 2 diabetes mellitus (T2DM).MethodsWe conducted an observational cohort study of adult patients (≥18 years) with T2DM undergoing abdominal surgery for pathologically confirmed CRC. Exclusion criteria included history of other malignancies, preoperative infections, or incomplete clinical data. Participants were stratified into two groups: the exposed group (CGM monitoring) and the control group (conventional glucose analyzer [CGA]). Primary outcomes included glycemic variability, surgical complications, ERAS milestones, and patient satisfaction scores.ResultsAmong 181 enrolled patients (CGM = 81, CGA = 100), CGM demonstrated superior glycemic control compared to CGA, with significantly lower mean daily glucose levels at postoperative day 1 (9.52 ± 2.53 vs. 10.37 ± 2.26 mmol/L, p < 0.05) and day 3 (9.36 ± 1.82 vs. 10.64 ± 1.84 mmol/L, p < 0.05). The CGM group showed better clinical outcomes including improved anastomotic healing (p < 0.05), shorter time to first flatus (p < 0.05), and reduced length of hospitalization (p < 0.05). Patient satisfaction scores were significantly higher in the CGM group (32.42 ± 3.33 vs. 29.81 ± 2.98, p < 0.05).ConclusionCGM provides superior perioperative glucose monitoring in diabetic CRC patients, particularly during the critical 72-h postoperative period. The technology facilitates early detection of acute hyperglycemia, promotes wound healing, and accelerates recovery within ERAS protocols. These findings support the clinical value of CGM implementation in surgical management of T2DM patients with CRC.https://www.frontiersin.org/articles/10.3389/fmed.2025.1464071/fullcontinuous glucose monitoringcolorectal cancerdiabetessurgeryERAS |
| spellingShingle | Qinbo Wang Qinbo Wang Qinbo Wang Yuan Zhou Yuan Zhou Wanzhen Wang Wanzhen Wang Yingjuan Ou Yingjuan Ou Yingjuan Ou Xia Wu Xia Wu Junrong Chen Junrong Chen Junrong Chen Xiaoyan Li Xiaoyan Li Hua Li Hua Li Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes) Frontiers in Medicine continuous glucose monitoring colorectal cancer diabetes surgery ERAS |
| title | Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes) |
| title_full | Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes) |
| title_fullStr | Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes) |
| title_full_unstemmed | Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes) |
| title_short | Effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes (application of CGM in the ERAS process of CRC patient with diabetes) |
| title_sort | effects of continuous glucose monitoring in enhanced recovery after colorectal cancer patient surgery with type 2 diabetes application of cgm in the eras process of crc patient with diabetes |
| topic | continuous glucose monitoring colorectal cancer diabetes surgery ERAS |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1464071/full |
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