Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway

Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway

Abstract Pathogenicity mechanisms of the yeast Candida albicans involve filamentous growth, adhesion, invasion, and toxin production. Interestingly, clinical isolates, and other Candida spp., can cause infection independent of filamentation or toxin production. These strains and species often are ch...

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Main Authors: Sophia U. J. Hitzler, Candela Fernández-Fernández, Kerstin Günther, Axel Dietschmann, Hrant Hovhannisyan, Anna Möslinger, Sophie Austermeier, Beatriz Cristóvão, Gianluca Vascelli, Teresa Zelante, Marina Pekmezović, Bernardo Ramírez-Zavala, Joachim Morschhäuser, Oliver Werz, Toni Gabaldón, Paul M. Jordan, Slavena Vylkova, Mark S. Gresnigt
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61701-5
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