Development and optimization of an injectable in-situ gel system for sustained release of anti-tuberculosis drugs

Development and optimization of an injectable in-situ gel system for sustained release of anti-tuberculosis drugs

Abstract Addressing the challenges of drug-resistant Mycobacterium tuberculosis requires regular drug intake and consistent therapeutic drug concentrations, for which in-situ gel systems offer a promising solution by enabling sustained drug release. This study aims to develop an injectable system fo...

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Bibliographic Details
Main Authors: Pooraniammal Balu, Srimari Srikanth, Divya Prakash Gnandhas, Ramya Devi Durai, Venkasubramanian Ulaganathan, Vedha Hari B Narayanan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-05644-3
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