Drug reaction with eosinophilia and systemic symptoms (DRESS) caused by sulfasalazine: a case report and literature review

Drug-induced hypersensitivity syndrome (DIHS) or drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, potentially fatal systemic reaction characterized by multiorgan damage involving the liver, hematopoietic system and skin, and heterogeneous manifestations of fever, rash, lympha...

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Bibliographic Details
Main Authors: A. S. Fedorov, Yu. O. Savelyeva, Yu. Yu. Grabovetskay, L. A. Rudyuk, E. M. Kuchinskaya, M. M. Kostik
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2024-04-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/1566
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Summary:Drug-induced hypersensitivity syndrome (DIHS) or drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, potentially fatal systemic reaction characterized by multiorgan damage involving the liver, hematopoietic system and skin, and heterogeneous manifestations of fever, rash, lymphadenopathy and eosinophilia with unpredictable course.We describe a 41-year-old female patient who developed DRESS syndrome after taking sulfasalazine prescribed for non-radiographic axial spondyloarthritis. Treatment with intravenous and then oral glucocorticoids was effective. A review of the literature on this topic is presented.
ISSN:1996-7012
2310-158X