First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, China

Two species of trichomonads, <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i>, are common intestinal parasites that can impact animal health and productivity. Severe infection by these parasites can lead to diarrhea and wasting in affected animals. Notably...

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Main Authors: Han-Dan Xiao, Shuo Zhang, Yi-Han Lv, Ze-Dong Zhang, Nan Su, Liang-Liang Li, Xing-Quan Zhu, Shi-Chen Xie, Wen-Wei Gao
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Language:English
Published: MDPI AG 2024-09-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/14/18/2651
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author Han-Dan Xiao
Shuo Zhang
Yi-Han Lv
Ze-Dong Zhang
Nan Su
Liang-Liang Li
Xing-Quan Zhu
Shi-Chen Xie
Wen-Wei Gao
author_facet Han-Dan Xiao
Shuo Zhang
Yi-Han Lv
Ze-Dong Zhang
Nan Su
Liang-Liang Li
Xing-Quan Zhu
Shi-Chen Xie
Wen-Wei Gao
author_sort Han-Dan Xiao
collection DOAJ
description Two species of trichomonads, <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i>, are common intestinal parasites that can impact animal health and productivity. Severe infection by these parasites can lead to diarrhea and wasting in affected animals. Notably, <i>P. hominis</i> is known to cause diarrhea and has the potential to be transmitted between animals and humans. Donkeys hold significant economic importance in China’s agricultural sector. However, whether donkeys are infected with <i>T. buttreyi</i> and <i>P. hominis</i> remains unknown globally. To address this gap in knowledge, 815 fecal samples were collected from donkeys in three representative regions in Shanxi Province, North China. Then, the presence and genetic characteristics of <i>T. buttreyi</i> and <i>P. hominis</i> were examined using species-specific PCR primers amplifying the small subunit ribosomal RNA genes. The overall prevalence was detected to be 25.4% (207/815) for <i>T. buttreyi</i> and 0.7% (6/815) for <i>P. hominis</i> in donkeys in Shanxi Province. All obtained <i>P. hominis</i> sequences were identified as genotype CC1. Genetic analysis revealed that all <i>P. hominis</i> isolates from donkeys were clustered into the same branch with isolates detected in humans, suggesting possible zoonotic transmission. This study is the first to report the occurrence and prevalence of <i>T. buttreyi</i> and <i>P. hominis</i> in donkeys globally. These findings expand the host range of trichomonads and improve our understanding of their genetic diversity and zoonotic potential, providing essential baseline data for the prevention and control of these parasites in donkeys in the region.
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spelling doaj-art-365c54fb60d74199890db39ce478e9df2025-08-20T01:56:04ZengMDPI AGAnimals2076-26152024-09-011418265110.3390/ani14182651First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, ChinaHan-Dan Xiao0Shuo Zhang1Yi-Han Lv2Ze-Dong Zhang3Nan Su4Liang-Liang Li5Xing-Quan Zhu6Shi-Chen Xie7Wen-Wei Gao8Laboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaTaiyuan Zoo, Taiyuan 030009, ChinaLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaLaboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, ChinaTwo species of trichomonads, <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i>, are common intestinal parasites that can impact animal health and productivity. Severe infection by these parasites can lead to diarrhea and wasting in affected animals. Notably, <i>P. hominis</i> is known to cause diarrhea and has the potential to be transmitted between animals and humans. Donkeys hold significant economic importance in China’s agricultural sector. However, whether donkeys are infected with <i>T. buttreyi</i> and <i>P. hominis</i> remains unknown globally. To address this gap in knowledge, 815 fecal samples were collected from donkeys in three representative regions in Shanxi Province, North China. Then, the presence and genetic characteristics of <i>T. buttreyi</i> and <i>P. hominis</i> were examined using species-specific PCR primers amplifying the small subunit ribosomal RNA genes. The overall prevalence was detected to be 25.4% (207/815) for <i>T. buttreyi</i> and 0.7% (6/815) for <i>P. hominis</i> in donkeys in Shanxi Province. All obtained <i>P. hominis</i> sequences were identified as genotype CC1. Genetic analysis revealed that all <i>P. hominis</i> isolates from donkeys were clustered into the same branch with isolates detected in humans, suggesting possible zoonotic transmission. This study is the first to report the occurrence and prevalence of <i>T. buttreyi</i> and <i>P. hominis</i> in donkeys globally. These findings expand the host range of trichomonads and improve our understanding of their genetic diversity and zoonotic potential, providing essential baseline data for the prevention and control of these parasites in donkeys in the region.https://www.mdpi.com/2076-2615/14/18/2651<i>Tetratrichomonas buttreyi</i><i>Pentatrichomonas hominis</i>donkeyprevalencezoonotic parasitesShanxi Province
spellingShingle Han-Dan Xiao
Shuo Zhang
Yi-Han Lv
Ze-Dong Zhang
Nan Su
Liang-Liang Li
Xing-Quan Zhu
Shi-Chen Xie
Wen-Wei Gao
First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, China
Animals
<i>Tetratrichomonas buttreyi</i>
<i>Pentatrichomonas hominis</i>
donkey
prevalence
zoonotic parasites
Shanxi Province
title First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, China
title_full First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, China
title_fullStr First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, China
title_full_unstemmed First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, China
title_short First Molecular Detection and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Donkeys in Shanxi Province, China
title_sort first molecular detection and genetic characterization of i tetratrichomonas buttreyi i and i pentatrichomonas hominis i in donkeys in shanxi province china
topic <i>Tetratrichomonas buttreyi</i>
<i>Pentatrichomonas hominis</i>
donkey
prevalence
zoonotic parasites
Shanxi Province
url https://www.mdpi.com/2076-2615/14/18/2651
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