Significant abundance of bacterial flagellin and expression of its surface localized receptor toll-like receptor 5 and cytokine interleukin-22 in South African infants with poor oral rotavirus vaccine take

Significant abundance of bacterial flagellin and expression of its surface localized receptor toll-like receptor 5 and cytokine interleukin-22 in South African infants with poor oral rotavirus vaccine take

Abstract Bacterial flagellin, a potent intestinal innate immune activator, prevents murine rotavirus (RV) infection independent of adaptive immunity and interferons. The flagellin-induced immunity is mediated by Toll-like receptor (TLR5) and Nod-like receptor C4 (NLRC4), which elicit the production...

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Bibliographic Details
Main Authors: Nontlantla J. Haindongo, Mapaseka Seheri, Cliff A. Magwira
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Gut Pathogens
Subjects:
Bacterial flagellin
Toll-like receptor 5
Nod-like receptor C4
Interleukin-22
Rotavirus vaccine
Shedding
Online Access:https://doi.org/10.1186/s13099-024-00672-2
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