Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Abstract Thoracic aortic dissection (TAD) is a life‐threatening condition with high mortality rates. Recent research suggests a potential link between early‐stage TAD and endothelial barrier dysfunction, although the underlying mechanisms remain unclear. Single‐cell RNA sequencing data from patients...

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Bibliographic Details
Main Authors: Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
Calpain‐2
focal adhesion
Itgav
Talin
thoracic aortic dissection
Online Access:https://doi.org/10.1002/advs.202501112
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